Protein Alignment alpha-Catr and Ctnna3

DIOPT Version :10

• Sequence 1: NP_726389.4
• Gene: alpha-Catr / 49713
• FlyBaseID: FBgn0029105
• Length: 810
• Species: Drosophila melanogaster
• Sequence 2: XP_038955205.1
• Gene: Ctnna3 / 361839
• RGDID: 1562230
• Length: 914
• Species: Rattus norvegicus
• Alignment Length: 853
• Identity: 174/853 - (20%)
• Similarity: 294/853 - (34%)
• Gaps: 243/853 - (28%)

  Fly    46 GEIIAEENIDIKGDMYEAAKEARDAGKSIERLCDISPLSGMELRHHIEP--LKDYGAIILAARSL 108
            ||:||:|...:|.|:..|.:|.|...|:         |.|...|...:|  |....|::.|||:|
  Rat    92 GEMIAKEATVLKEDLEAALQEVRKESKA---------LKGSAERFTDDPCYLPKREAVVQAARAL 147

  Fly   109 LSSVTRILLLVDIIVVKKLLTAKKRASESLEKLESVMNFTEFVRAFSVFGTEMIELAYLTGHHRN 173
            |::|||:|:|.|:..|..||........:.:.|::|.|.::..:.:...|.|:..|.......:.
  Rat   148 LAAVTRLLILADMTDVMCLLQHVSSFQRTFKSLKNVSNKSDLQKTYQKLGKELERLDRFAFKRQQ 212

  Fly   174 SFKEERRRAQMFSARQILEKSIAILLTSSKNSLIHSDCVIVKENRDTVFCQIRRAMDLIHFVVKD 238
            ..|...:|.::..||..|:::..:|.:.....|.|||...:|.::|||..:|:.|:|:|
  Rat   213 DLKSPSQRDEIAGARATLKENSPLLHSICSACLEHSDVASLKASKDTVCEEIQNALDVI------ 271

  Fly   239 SIFDTAKHMPFEKQASNPNYENESIYTTIKRIVNLIKRYKYQMSYYEGSGEGNNNSDAYFSFLDD 303
                           ||                               :.:|..|..|...
  Rat   272 ---------------SN-------------------------------ASQGIQNVPASLE---- 286

  Fly   304 DLWKSEKNLPSAAGGGRMVN---NTNFRKHLSSESLDLREELSLAFEKLFEKAHDFTDSPYISHN 365
                     |.||..|..::   |......|:....|||..|....|.:...|....||......
  Rat   287 ---------PQAATLGSALDELENLIVLNPLTVTEEDLRPPLEKRLEAIISGAALLADSSCTRDL 342

  Fly   366 HRKNILSYCDNCKLEF-DL---YLNTIMKDQHEGGGGAGGVGGVGGGQVKGRSDPELGMLSSLEE 426
            ||:.|::.|:..:... ||   |::.|.|.:.........|                .|.....:
  Rat   343 HRERIIAECNAIRQALQDLLSEYMSNIGKTERSNTLNTAIV----------------NMSKKTRD 391

  Fly   427 LCKQLVVSVSSQIED-FNESLKICSKLVKSFHVLATNYDIDNLNQRSSKFHDCCDHIFDICKLLQ 490
            |.:||..::...|.| |.::......|:::    |.|..:..:...:|.||:....:.::..|..
  Rat   392 LRRQLRKAIIDHISDSFLDTTVPLLVLIEA----AKNGQVKEIKDYASIFHEHTGRLMEVANLAC 452

  Fly   491 HIAPTERLQVQAKCLAINLRIYGPQVFIAAKILWKYSNSSAANENFESFSDMWKW----LT---N 548
            .::..|......:..|.:|....||:..||..|.....|.......|.:...|:.    ||   :
  Rat   453 SMSTNEDGIKIVRIAANHLETLCPQIINAALALASRPKSQVVKNTMEMYKRTWEHYIHVLTEAVD 517

  Fly   549 EISMIAKKILVSINTTKGD--------RDADAEKCESSS-------------------------- 579
            :|:.|...:.||.:....|        ||.||:..:.::
  Rat   518 DITSIDDFLAVSESHILEDVNRCIIALRDQDADNLDRAAGAIRGRAARVAHIVAGEMDSYEPGAY 582

  Fly   580 ---------------------------DKLTKSGVPATEDGEMVEYS------------------ 599
                                       |.|:|:.:.|.:|.:.|:.|
  Rat   583 TEGVMRNVNLLTSIVIPEFVTQVNVALDALSKNALTALDDNQFVDISKKIYDTIHDIRCSVMIIR 647

  Fly   600 -----------------------GLEGKNN-------------------GDLNTYQSKWSEDLS- 621
                                   ..|||.:                   .|....:||...::.
  Rat   648 TPEELEDVSDLEDDHEVRSHTSTQTEGKTDRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEI 712

  Fly   622 -DD--NDILKRAKNMSAMAFLMYQFTKGNGSLRTTQDLFTQAEYFAEEANRLYKVLRHFSYQVPA 683
             ||  |||:..||.|..:...|..||:|.|.|:.|.|:...|:..:|..:|:..:.|..:.|.|.
  Rat   713 WDDTSNDIIVLAKKMCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPD 777

  Fly   684 SDNKKDLLNILDRVPTFVQAL----QFTVKDHTVGKAATFVKVDHV---IRETKNLMNVINKVVS 741
            ...|:|||..|:::..:...|    |...:...:|.......:|.|   |:..|||||.:.:.|.
  Rat   778 PPCKQDLLAYLEQIKFYSHQLKICSQVKAEIQNLGGELIVSALDSVTSLIQAAKNLMNAVVQTVK 842

  Fly   742 KCFECATK 749
            ..:..:||
  Rat   843 MSYIASTK 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Catr	NP_726389.4	Vinculin	38..755	CDD:460040	174/853 (20%)
Ctnna3	XP_038955205.1	Vinculin	37..875	CDD:460040	174/853 (20%)