Protein Alignment alpha-Catr and ctnna1

DIOPT Version :9

• Sequence 1: NP_726389.4
• Gene: alpha-Catr / 49713
• FlyBaseID: FBgn0029105
• Length: 810
• Species: Drosophila melanogaster
• Sequence 2: NP_571531.1
• Gene: ctnna1 / 30741
• ZFINID: ZDB-GENE-991207-24
• Length: 907
• Species: Danio rerio
• Alignment Length: 888
• Identity: 190/888 - (21%)
• Similarity: 316/888 - (35%)
• Gaps: 264/888 - (29%)

  Fly    38 AVERFITIGEIIAEENIDIKGDMYEAAKEARDAGKSIERLCDISPLSGMELRHHIEPLKDYGAII 102
            |.:.|:..||.||:|:..:|.::..|.::.|..|:|::.      .||.........:| .|.::
Zfish    68 ATQNFLEKGEKIAKESQFLKEELTAAVEDVRKQGESMKM------ASGEFAEDPCSSVK-RGNMV 125

  Fly   103 LAARSLLSSVTRILLLVDIIVVKKLLTAKKRASESLEKLESVMNFTEFVRAFSVFGTEMIELAYL 167
            .|||:|||:||.:|:|.|:..|.:||...|...|:|.|:.:.....:....:.....|:.:|..:
Zfish   126 RAARALLSAVTHLLVLADMADVYQLLLQLKLVEENLMKVRNAGTEQDLGIQYKALKPEVDKLNMM 190

  Fly   168 TGHHRNSFKEERRRAQMFSARQILEKSIAILLTSSKNSLIHSDCVIVKENRDTVFCQIRRAMDLI 232
            ....:...|:...:.||.:||.:|::::.:|.|:|:..|.|.|....|.|||.::.|::.|:..|
Zfish   191 AAKRQQELKDVHHKDQMAAARGVLQRNVPMLYTASRACLQHPDVAAYKANRDLIYKQLQHAVSGI 255

  Fly   233 HFVVKDSIFDTAKHMPFEKQASNPNYENESIYTTIKRIVNLIKRYKYQMSYYEGSGEGNNNSDAY 297
                                 ||                               :.:..::.|:.
Zfish   256 ---------------------SN-------------------------------AAQATSSEDSS 268

  Fly   298 FSFLDDDLWKSEKNLPSAAGGGRMVNN-TNFRKHLSSESLDLREE-----LSLAFEKLFEKAHDF 356
            ||              ..||||.:... .||.|.:..:.|...||     |....|.:...|...
Zfish   269 FS--------------QTAGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEERLESIISGAALM 319

  Fly   357 TDSPYISHNHRKNILSYCDNCKLEFDLYLNTIMKDQHEGGGGAGGVGGVGGGQVKGRSDPELG-- 419
            .||.....:.|:.|::.|::.:......|:..|       |.||.         |.:|| .|.
Zfish   320 ADSSCTRDDRRERIVAECNSVRQALQDLLSEYM-------GNAGR---------KEKSD-ALNTA 367

  Fly   420 ---MLSSLEELCKQLVVSVSSQIED-FNESLKICSKLVKSFHVLATNYDIDNLNQRSSKFHDCCD 480
               |.....:|.:||..:|...:.| |.|:......|:::    |.|.:...:.:.:..|.:..:
Zfish   368 IDRMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEA----AKNGNEKEVKEYAQVFREHAN 428

  Fly   481 HIFDICKLLQHIAPTERLQVQAKCLAINLRIYGPQVFIAAKILWKYSNSSAANENFESFSDMW-- 543
            .:.::..|...|:..|......:..|..|....|||..||..|....||..|.:|.:.|.|.|
Zfish   429 KLIEVANLACSISNNEEGVKLVRMAASQLETLCPQVINAALALAAKPNSKVAQDNMDLFKDQWEK 493

  Fly   544 --KWLT---NEISMIAKKILVSINTTKGD----------RDAD---------------------- 571
              :.||   ::|:.|...:.||.|....|          :|.|
Zfish   494 QVRVLTDAVDDITSIDDFLCVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRGRAARVVHVVTS 558

  Fly   572 -----------------------------AEKCESSSDKLT-KSGVPATE----DGEMVEYSGL- 601
                                         .|:.|::.:.|: .:|.|..|    |...:.|.|:
Zfish   559 EMDNYMPGVYTEKVLEATKLLTETVMPRFTEQVEAAVEALSANNGQPVDENEFIDASRLVYDGVR 623

  Fly   602 ------------EGKNNGDLNT------------------------------------------- 611
                        |..::.|..|
Zfish   624 DIRKAVLMIRTPEELDDSDFETEDFDSRSRTSVQTEDDQLIAGQSARAIMAQLPQEQKAKIAEQV 688

  Fly   612 --YQ----------SKWSEDLSDDNDILKRAKNMSAMAFLMYQFTKGNGSLRTTQDLFTQAEYFA 664
              :|          |||.:   ..|||:..||.|..:...|..||:|.|.|:.|.|:.:.|:..|
Zfish   689 ASFQEEKSKLDAEVSKWDD---SGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVISAAKKIA 750

  Fly   665 EEANRLYKVLRHFSYQVPASDNKKDLLNILDRVPTFVQALQFTVK----DHTVGKAATFVKVD-- 723
            |..:|:.|:.|..:.|.|.|..|:|||..|.|:..|...|....|    ...:|.......:|
Zfish   751 EAGSRMDKLGRAIADQCPDSACKQDLLAYLQRIALFCHQLNICSKVKAEVQNLGGELVVSGLDSA 815

  Fly   724 -HVIRETKNLMNVINKVVSKCFECATKYK-------LNLTGIT 758
             .:|:..|||||.:...|...:..:|||:       ||:..|:
Zfish   816 MSLIQAAKNLMNSVVSTVKASYVASTKYQKSQDMQSLNMPAIS 858

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Catr	NP_726389.4	Vinculin	52..755	CDD:279395	183/869 (21%)
ctnna1	NP_571531.1	Vinculin	82..867	CDD:279395	184/874 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910