Protein Alignment alpha-Catr and hmp-1

DIOPT Version :9

• Sequence 1: NP_726389.4
• Gene: alpha-Catr / 49713
• FlyBaseID: FBgn0029105
• Length: 810
• Species: Drosophila melanogaster
• Sequence 2: NP_001122991.1
• Gene: hmp-1 / 179624
• WormBaseID: WBGene00001978
• Length: 930
• Species: Caenorhabditis elegans
• Alignment Length: 895
• Identity: 158/895 - (17%)
• Similarity: 284/895 - (31%)
• Gaps: 276/895 - (30%)

  Fly    35 LNIAVERFITIGEI------IAEEN---IDIKGDMYEAAKEARDAGKSIERLCDISPLSGMELRH 90
            |:.||..|:..|..      ||..:   ||:   ::||....:|.|:       :...:|.:...
 Worm    54 LDAAVANFLQTGSFAISKCPIANSDPRAIDL---LHEALGAVQDTGQ-------VMIQTGRDFVR 108

  Fly    91 HIEPLKDYGAIILAARSLLSSVTRILLLVDIIVVKKLLTAKKRASESLEKLESVMNFTEFVRAFS 155
            .............:.|:||::|.:.|:|.|.|.||.::.......|:..::.......:....::
 Worm   109 DSTSTNKRAIATNSGRNLLTAVAKFLILADSIDVKVIVDKVDEVRETAHQMIEADTKIKVDDLYN 173

  Fly   156 VFGTEMIELAYLTGHHRNSFKEERRRAQMFSARQILEKSIAILLTSSKNSLIHSDCVIVKENRDT 220
            :..:::.||............:..:|..:.:||..|.::..:|.||::..:.|.:....:.|||.
 Worm   174 LLISQIEELDITVRRRAIDLVKPNQRDDLLAARSALRQTAPLLYTSTRTFVRHPEHEEARRNRDY 238

  Fly   221 VFCQIRRAMDLIHFVVKDSIFDTAKHMPFEKQASNPNYENESIYTTIKRIVNLIKRYKYQMSYYE 285
            ...::..|::.:..|:..                                    ::.|...|.|.
 Worm   239 TADEMHSALNALESVLNG------------------------------------QQPKVTFSEYG 267

  Fly   286 GSGEGNNNSDAYFSFLDDDLWKSEKNLPSAAGGGRMVNNTNFRKHLSSESLDLREELSLAFEKLF 350
            ..|:..|..|.:.:.::                   ::..::|:...      |.:|....|::.
 Worm   268 RIGDLINEIDTFQNRIE-------------------IDPAHYRRGTD------RPDLEGHCERIV 307

  Fly   351 EKAHDFTDSPYISHNHRKNILSYCDNCKLEFDLYLNTIMKDQHEGGGGAGGVGGVGGGQVKGRSD 415
            ..:....|:.....|.::.|::.|:|.:......|....|..               |:.....|
 Worm   308 SGSASIADAESTRENRKQKIVAECNNLRQALQELLTEYEKST---------------GRRDDNDD 357

  Fly   416 PELGMLSSLEELCKQL--------VVSVSSQIEDFNESLKICSKLVKSFHVLATNYDIDNLNQRS 472
            ..|| ::.:.:..|.|        |..:|....|....|.:..:..|..|...|.|       ||
 Worm   358 IPLG-IAEVHKRTKDLRRHLRRAIVDHISDAFLDTRTPLILLIEAAKEGHEENTRY-------RS 414

  Fly   473 SKFHDCCDHIFDICKL-LQHIAPTERLQVQAKCLAINLRIYGPQVFIAAKILWKYSNSSAANENF 536
            ..|.:..:.|..:.:| .|..:..|.:.| .:..|..|....|||..||.:|.....|..|.||.
 Worm   415 KMFQEHANEIVSVARLSCQLSSDVESVSV-IQHTAAQLEKLAPQVAQAAILLCHQPTSKTAQENM 478

  Fly   537 ESFSDMW----KWLTNEISMI-----------------AKKILVSINTTKGDRDADAEKCE---- 576
            |::.:.|    :.||..:..|                 .::.:..|.......|.:|..||
 Worm   479 ETYKNAWFDKVRLLTTALDNITTLDDFLAVSEAHIVEDCERGIKGITANASTPDENAANCETVDC 543

  Fly   577 -------------------------SSSDKLTKSGV----------------------------- 587
                                     |...:..|..|
 Worm   544 AAGSIRGRALRVCDVVDAEMDFLQNSEYTETVKQAVRILKTQRVDQFAERASALANRQEAHGLTW 608

  Fly   588 -PATEDGEMVEY----------------------------SGLE------GKNNGDLNTYQS--- 614
             |.|::.||.|:                            |.:|      |..|.|.|...|
 Worm   609 DPKTKEEEMNEFINACTLVHDAVKDIRHALLMNRSMNDVDSDVEYEADGVGAANADANRTISEQE 673

  Fly   615 ------------------------------------KWSEDLSDDNDILKRAKNMSAMAFLMYQF 643
                                                ||.|   ..|||:..|.||..:...|.:|
 Worm   674 NQQNLMRRLPEEEKKKIQAQIDIFKVTQTRFEREVAKWDE---TGNDIISLANNMCKIMMSMTEF 735

  Fly   644 TKGNGSLRTTQDLFTQAEYFAEEANRLYKVLRHFSYQVPASDNKKDLLNILDRVPTFVQALQFTV 708
            |:|.|.|:||.|:...|:..:...::|..:.|....:...|..|||||..|.::..:.|.|....
 Worm   736 TRGCGPLKTTMDVIRAAQEISLNGSKLNALARQIGEESADSQTKKDLLAYLSQITLYCQQLNICS 800

  Fly   709 K---DHT-VGKAATFVKVD---HVIRETKNLMNVINKVVSKCFECATKYK 751
            |   |.| ||.......:|   .:|:..:||:..:.:.|...:..:||::
 Worm   801 KVKADVTQVGNELVVSALDSAMSLIQTARNLLTAVVQTVKAAYIASTKFR 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Catr	NP_726389.4	Vinculin	52..755	CDD:279395	151/872 (17%)
hmp-1	NP_001122991.1	Vinculin	77..869	CDD:279395	151/872 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910