DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gish and ckl7

DIOPT Version :9

Sequence 1:	NP_001262624.1	Gene:	gish / 49701	FlyBaseID:	FBgn0250823	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001330873.1	Gene:	ckl7 / 834433	AraportID:	AT5G44100	Length:	476	Species:	Arabidopsis thaliana

Alignment Length:	484	Identity:	204/484 - (42%)
Similarity:	278/484 - (57%)	Gaps:	86/484 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 LMVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLL--GSHADN 118
            |::|..|::|||||.|:||||.||.|:...|.||:|:|.:|:|.||||.|.:.|.||  ||
plant     3 LVIGGKFKLGKKIGSGSFGELYLGVNVQTGEEVAVKLENVKTKHPQLHYESKLYMLLQGGS---- 63

  Fly   119 APDGIPRIYHLGTCGGRYNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHL 183
               |||.|...|. .|.|:.||::|||.|||||||.|.||.:||||||:|.|||:|:|::|:|..
plant    64 ---GIPNIKWFGV-EGDYSVMVIDLLGPSLEDLFNYCNRKLTLKTVLMLADQLLNRVEFMHTRGF 124

  Fly   184 IYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMG 248
            ::||:||:|||:|  ..::...::||||||.|:|.||.|::||||||:|:|||||||.|:|||:|
plant   125 LHRDIKPDNFLMG--LGRKANQVYIIDFGLGKKYRDLQTHKHIPYRENKNLTGTARYASVNTHLG 187

  Fly   249 REQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYL 313
            .|||||||||:||::.||||:||||||||||.|.|::|.:|.:.|.:|||||||...|.||.:|.
plant   188 VEQSRRDDLESLGYVLMYFLKGSLPWQGLKAGTKKQKYDRISEKKVSTPIEVLCKNQPSEFVSYF 252

  Fly   314 RYVRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDWTGKTMSTP-VGSLQTGHEVIISPNKDR 377
            .|.|.|.|.:.|||.:|:|||:|||.|:||..:..||||  .:..| :|| .:|     |.::.|
plant   253 HYCRSLRFDDKPDYSYLKRLFRDLFIREGYQFDYVFDWT--VLKYPQIGS-SSG-----SSSRTR 309

  Fly   378 HNVTAKTNAKGGVAAWPDVPKPGATLGNLTPADRHGSVQVVSSTNGELNPDDPTAGHSNTPITQQ 442
            |:.||               |||                        .|.|         ||.:|
plant   310 HHTTA---------------KPG------------------------FNAD---------PIERQ 326

  Fly   443 PEVEVVDETKCCCFFKRKKKKSTRQKXLDGVQCSPEREAVTLLRATSHSNSRDSVLNNP--SQDY 505
            ..:              ..|::||.|....|:....|...|.......|.||:|. :.|  .|.:
plant   327 ERI--------------LGKETTRYKIPGAVEAFSRRHPTTTSSPRDRSRSRNSD-DGPFSKQTH 376

  Fly   506 IQQATSQHTLRYPPSASMLTPTPTTNTPT 534
            .....:..:.||..|:|......:::.|:
plant   377 GDSERANSSSRYRASSSRKAVAASSSRPS 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	167/294 (57%)
		S_TKc	62..335	CDD:214567	156/274 (57%)
		CK1gamma_C	354..428	CDD:289378	13/74 (18%)
ckl7	NP_001330873.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	161/283 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11909
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910