Protein Alignment gish and ckl8

DIOPT Version :10

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_199146.1
• Gene: ckl8 / 834350
• AraportID: AT5G43320
• Length: 480
• Species: Arabidopsis thaliana
• Alignment Length: 505
• Identity: 211/505 - (41%)
• Similarity: 291/505 - (57%)
• Gaps: 68/505 - (13%)

  Fly    57 MVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAPD 121
            :||..:::|:|:|.|:||||.||.|:...|.||:|:||.:::.||||.|.:.|.||     ....
plant     4 VVGGKYKLGRKLGSGSFGELFLGVNVQTGEEVAVKLEPARARHPQLHYESKLYMLL-----QGGT 63

  Fly   122 GIPRIYHLGTCGGRYNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIYR 186
            |||.:...|. .|.||.||::|||.|:|||||.|:|:|:||||||:|.|:::|:||:|.|..::|
plant    64 GIPHLKWYGV-EGEYNCMVIDLLGPSMEDLFNYCSRRFNLKTVLMLADQMINRVEYMHVRGFLHR 127

  Fly   187 DVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQ 251
            |:||:|||:|  ..::...::|||:||||:|.||.|:|||||||:|:|||||||.|:|||:|.||
plant   128 DIKPDNFLMG--LGRKANQVYIIDYGLAKKYRDLQTHRHIPYRENKNLTGTARYASVNTHLGIEQ 190

  Fly   252 SRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRYV 316
            |||||||:||::.|||||||||||||:|.|.|::|.||.:.||.||:||||...|.||.:|..||
plant   191 SRRDDLESLGYVLMYFLRGSLPWQGLRAGTKKQKYDKISEKKRLTPVEVLCKSFPPEFTSYFLYV 255

  Fly   317 RRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDWTGKTMSTPVGSLQTGHEVIISPNKDRHNVT 381
            |.|.|.:.|||.:|:|||:|||.|:||..:..||||  .:..|  ...:|..   |.:|.|.::.
plant   256 RSLRFEDKPDYPYLKRLFRDLFIREGYQFDYVFDWT--ILKYP--QFSSGSS---SSSKPRSSLR 313

  Fly   382 AKTNAKGGVAAWPDVPKPGATLGNLTPADR-HGSVQVVSSTNGE------------LNPDDPTAG 433
            ...|....:|..||.|..||   .....|| .|:::..:..||.            ...::..|.
plant   314 PAMNPPVPIAERPDKPSAGA---GQDSRDRFSGALEAYARRNGSGSGVVQADRSRPRTSENVLAS 375

  Fly   434 HSNTPITQQPEVEVVDETKCCCFFKRKKKKSTRQKXLDGVQCSPEREAVTLLRATSHSNSRDSVL 498
            ..:|.......||             :...|||..       |..:..|:.:||||   |.|...
plant   376 SKDTTPQNYERVE-------------RPISSTRHAS------SSRKAVVSSVRATS---SADFTE 418

  Fly   499 NN-----PSQDYIQQATSQHTLRYP-----PSASMLT---PTPTTNTPTL 535
            |.     ||..  :.:|:|.|...|     ||:|..|   |:.|....||
plant   419 NRSSRVVPSNG--RSSTAQRTQLVPDPTTRPSSSSFTRAAPSRTARDITL 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	162/292 (55%)
		CK1gamma_C	354..439	CDD:463640	19/97 (20%)
ckl8	NP_199146.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	156/281 (56%)
		PHA03307	318..>461	CDD:223039	38/169 (22%)