Protein Alignment gish and Csnk1g2

DIOPT Version :10

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: XP_006241063.1
• Gene: Csnk1g2 / 65278
• RGDID: 621407
• Length: 441
• Species: Rattus norvegicus
• Alignment Length: 454
• Identity: 292/454 - (64%)
• Similarity: 336/454 - (74%)
• Gaps: 57/454 - (12%)

  Fly    35 GKSSSNNMYSTRQSVSTTTGVLMVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKA 99
            |.:.||  :..|.| .|::||||||||||||||||||||||||||||||.||:||||:||:||:|
  Rat    22 GTNRSN--HGVRNS-GTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRA 83

  Fly   100 PQLHLEYRFYK--------------LLGSHADNAP-------DGIPRIYHLGTCGGRYNAMVLEL 143
            |||||||||||              |||......|       :|:|::|:.|.| |:||||||||
  Rat    84 PQLHLEYRFYKQLSTTGEDTGRGAALLGGQGLRTPSIDVSLAEGVPQVYYFGPC-GKYNAMVLEL 147

  Fly   144 LGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHI 208
            ||.||||||::|.|.|:||||||||.||:.|:||||::.||||||||||||:||..:||:..|||
  Rat   148 LGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHI 212

  Fly   209 IDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQSRRDDLEALGHMFMYFLRGSLP 273
            |||||||||||.:|.:||||||||||||||||||||||:|:||||||||||||||||||||||||
  Rat   213 IDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLP 277

  Fly   274 WQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRYVRRLDFFETPDYDFLRRLFQDLF 338
            |||||||||||||||||||||||||||||:..|||.||||||||||||||.||||:||:||.|||
  Rat   278 WQGLKADTLKERYQKIGDTKRATPIEVLCESFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLF 342

  Fly   339 DRKGYTDEGEFDWTGKTMSTPVGSLQTGHEVIISPNKDRHNVTAKTNAKGGVAAWPDVPKPGATL 403
            ||.||..:.|:||.||.:.||:|::.                             ||||....
  Rat   343 DRSGYVFDYEYDWAGKPLPTPIGTVH-----------------------------PDVPSQPP-- 376

  Fly   404 GNLTPADRHGSVQVVSSTNGELNPDDPTAGHSNTPITQQPEVEVVDETKCCCFFKRKKKKSTRQ 467
             :...|..|...|.::|||||||.|||||||||.||....||||.|||||||||||:|:||.::
  Rat   377 -HRDKAQLHTKNQALNSTNGELNTDDPTAGHSNAPIAAPAEVEVADETKCCCFFKRRKRKSLQR 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	231/313 (74%)
		CK1gamma_C	354..439	CDD:463640	27/84 (32%)
Csnk1g2	XP_006241063.1	STKc_CK1_gamma	45..358	CDD:271028	231/313 (74%)
		CK1gamma_C	358..411	CDD:463640	27/84 (32%)