Protein Alignment gish and csnk1g2b

DIOPT Version :10

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001039315.1
• Gene: csnk1g2b / 561724
• ZFINID: ZDB-GENE-060825-285
• Length: 444
• Species: Danio rerio
• Alignment Length: 471
• Identity: 298/471 - (63%)
• Similarity: 354/471 - (75%)
• Gaps: 48/471 - (10%)

  Fly    10 GGGPQTTTAGPSAGNVANATTALAGGKSSSNNMYSTRQSVSTTTGVLMVGPNFRVGKKIGCGNFG 74
            ||..:|    .....::..|.:..||:.:.|            :|||||||||||||||||||||
Zfish     7 GGKGET----EEVKKMSKPTGSRTGGRGTGN------------SGVLMVGPNFRVGKKIGCGNFG 55

  Fly    75 ELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAPDGIPRIYHLGTCGGRYNAM 139
            |||||||||.||:||||:||:||:||||||||||||.||:     .:|:|::::.|.| |:||||
Zfish    56 ELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGN-----SEGVPQVFYFGPC-GKYNAM 114

  Fly   140 VLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREK 204
            ||||||.||||||::|.|.||||||||||.||:.|:|:||:|.||||||||||||:||..:||:.
Zfish   115 VLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLITRMEFVHTRSLIYRDVKPENFLMGRPGSKRQH 179

  Fly   205 IIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQSRRDDLEALGHMFMYFLR 269
            .||||||||||||||.:|.:||||||||||||||||||||||:|:||||||||||||||||||||
Zfish   180 TIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLR 244

  Fly   270 GSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRYVRRLDFFETPDYDFLRRLF 334
            |||||||||||||||||||||||||||||||||:..|||.||||||||||||||.|||::||:||
Zfish   245 GSLPWQGLKADTLKERYQKIGDTKRATPIEVLCESFPEEMATYLRYVRRLDFFERPDYEYLRKLF 309

  Fly   335 QDLFDRKGYTDEGEFDWTGKTMSTPVGSLQTGHEVIISPNKDRHNVTAKTNAKGGVAAWPDVPKP 399
            .|||||.|:..:.|:||.||.:.||:|.:.|...   .|::|:.....|..:          |:|
Zfish   310 TDLFDRNGFVFDFEYDWVGKPLPTPIGPIPTDTP---QPSRDKAQPQTKNQS----------PEP 361

  Fly   400 ------------GATLGNLTPADR-HGSVQVVSSTNGELNPDDPTAGHSNTPITQQPEVEVVDET 451
                        ..|||:...|:| .|||||:||||||||.|||||||||.|||...||||.|:|
Zfish   362 KRSESQPTPVTNRETLGSQVTAERLGGSVQVMSSTNGELNTDDPTAGHSNAPITAPAEVEVADDT 426

  Fly   452 KCCCFFKRKKKKSTRQ 467
            ||||||||:|:|:.::
Zfish   427 KCCCFFKRRKRKALQR 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	227/292 (78%)
		CK1gamma_C	354..439	CDD:463640	37/97 (38%)
csnk1g2b	NP_001039315.1	STKc_CK1_gamma	42..329	CDD:271028	227/292 (78%)
		CK1gamma_C	329..414	CDD:463640	37/97 (38%)