Protein Alignment gish and csnk1g2

DIOPT Version :10

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: XP_012817061.1
• Gene: csnk1g2 / 548442
• XenbaseID: XB-GENE-481191
• Length: 412
• Species: Xenopus tropicalis
• Alignment Length: 467
• Identity: 286/467 - (61%)
• Similarity: 341/467 - (73%)
• Gaps: 59/467 - (12%)

  Fly     2 QRRERQASGGGPQTTTAGPSAGNVANATTALAGGKSSSNNMYSTRQSVSTTTGVLMVGPNFRVGK 66
            ||.|:    |.|:......|...|       ..|:||.|        .:..:|||||||||||||
 Frog     5 QREEK----GDPEEVARRMSKSGV-------GPGRSSRN--------TAANSGVLMVGPNFRVGK 50

  Fly    67 KIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAPDGIPRIYHLGT 131
            |||||||||||||||||.||:||||:||:||:||||||||||||.||:     .:|:|::|:.|.
 Frog    51 KIGCGNFGELRLGKNLYTNEYVAIKLEPVKSRAPQLHLEYRFYKQLGN-----TEGLPQVYYFGP 110

  Fly   132 CGGRYNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIYRDVKPENFLIG 196
            | |:||||||||||.||||||::|.|.|:||||||||.||:.|:||||::.|:||||||||||:|
 Frog   111 C-GKYNAMVLELLGPSLEDLFDLCNRTFTLKTVLMIAVQLISRMEYVHAKSLVYRDVKPENFLLG 174

  Fly   197 RTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQSRRDDLEALG 261
            |..:||:|.||||||||||||.|.:|.:||||||||||||||||||||||:|:||||||||||||
 Frog   175 RPGSKRQKTIHIIDFGLAKEYWDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALG 239

  Fly   262 HMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRYVRRLDFFETPD 326
            |||||||||:|||||||||||||||||||||||.||:|:||:..|||.||||||||:|||||.||
 Frog   240 HMFMYFLRGNLPWQGLKADTLKERYQKIGDTKRTTPVEILCNNFPEELATYLRYVRQLDFFEKPD 304

  Fly   327 YDFLRRLFQDLFDRKGYTDEGEFDWTGKTMSTPVGSLQTGHEVIISPNKDRHNVTAKTNAKGGVA 391
            |::|||||.||.||:|...:.|:||.|||:.:|:||:..|....:...|..:.
 Frog   305 YEYLRRLFTDLLDRRGLIFDYEYDWVGKTLPSPIGSVPYGGLTQVQSKKQLYL------------ 357

  Fly   392 AWPDVPKPGATLGNLTPADRHGSVQVVSSTNGELNPDDPTAGHSNTPITQQPEVEVVDETKCCCF 456
                               :|   |.::||||:||.|||||||||.|||....|||.|:||||||
 Frog   358 -------------------KH---QGLNSTNGDLNMDDPTAGHSNAPITAHTGVEVADDTKCCCF 400

  Fly   457 FKRKKKKSTRQK 468
            |||:|:|||:||
 Frog   401 FKRQKRKSTQQK 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	221/292 (76%)
		CK1gamma_C	354..439	CDD:463640	24/84 (29%)
csnk1g2	XP_012817061.1	STKc_CK1_gamma	45..332	CDD:271028	221/292 (76%)
		CK1gamma_C	<344..383	CDD:463640	19/72 (26%)