DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gish and csnk1g1

DIOPT Version :9

Sequence 1:	NP_001262624.1	Gene:	gish / 49701	FlyBaseID:	FBgn0250823	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	XP_031753667.1	Gene:	csnk1g1 / 448124	XenbaseID:	XB-GENE-488259	Length:	460	Species:	Xenopus tropicalis

Alignment Length:	442	Identity:	299/442 - (67%)
Similarity:	347/442 - (78%)	Gaps:	25/442 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 YSTRQSVSTT-TGVLMVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEY 106
            :|:|.|.||| :||||||||||||||||||||||||||||||.||:||||:||:||:||||||||
Frog    24 HSSRPSSSTTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEY 88

  Fly   107 RFYKLLGSHADNAPDGIPRIYHLGTCGGRYNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQL 171
            ||||.||    |..:|:|::::.|.| |:||||||||||.||||||::|.|.|:||||||||.||
Frog    89 RFYKQLG----NTAEGLPQVFYFGPC-GKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQL 148

  Fly   172 LHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTG 236
            :.|:|||||::|||||||||||||||...|:|.|||||||||||||||.:|.:||||||||||||
Frog   149 ISRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHIIHIIDFGLAKEYIDPETKKHIPYREHKSLTG 213

  Fly   237 TARYMSINTHMGREQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 301
            ||||||||||:|:|||||||||||||||||||||||||||||||||||||||||||||.||:|||
Frog   214 TARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPVEVL 278

  Fly   302 CDGHPEEFATYLRYVRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDWTGKTMSTPVGSLQT- 365
            |:..|||.||||||||||||||.||||:||.||.:||:||||:.:..:||.|:.:.||.||:..
Frog   279 CENFPEEMATYLRYVRRLDFFEKPDYDYLRTLFSELFERKGYSFDYVYDWVGRPIPTPGGSVHVD 343

  Fly   366 -----------GHEVIISPNKDRHNVTAKTNAKGGVAAWPDVPKPGATLGNLTP---ADRH-GSV 415
                       ||....|..:...|.|...:.:|   ||.......|....|.|   :||| |||
Frog   344 SGTSAITRESHGHRERPSQTQPLRNQTGVPDRRG---AWDLQVGRQAHPAYLVPHLASDRHGGSV 405

  Fly   416 QVVSSTNGELNPDDPTAGHSNTPITQQPEVEVVDETKCCCFFKRKKKKSTRQ 467
            ||:|||||:||.||.|.||||.|||.|.|||||:|.|||||||||:|..:::
Frog   406 QVMSSTNGQLNADDQTGGHSNAPITAQAEVEVVEEAKCCCFFKRKRKNHSQR 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	228/292 (78%)
		S_TKc	62..335	CDD:214567	218/272 (80%)
		CK1gamma_C	354..428	CDD:289378	30/89 (34%)
csnk1g1	XP_031753667.1	STKc_CK1_gamma	43..331	CDD:271028	228/292 (78%)
csnk1g1	XP_031753667.1	CK1gamma_C	331..429	CDD:403712	37/100 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	360	1.000	Domainoid score	I955
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	574	1.000	Inparanoid score	I1032
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D281034at33208
OrthoFinder	1	1.000	-	-		FOG0001189
OrthoInspector	1	1.000	-	-		oto105232
Panther	1	1.100	-	-	O	PTHR11909
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X651
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.160