Protein Alignment gish and Asator

DIOPT Version :10

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_651924.2
• Gene: Asator / 43794
• FlyBaseID: FBgn0039908
• Length: 1349
• Species: Drosophila melanogaster
• Alignment Length: 565
• Identity: 150/565 - (26%)
• Similarity: 239/565 - (42%)
• Gaps: 115/565 - (20%)

  Fly    46 RQSVSTTTGVLM-----VGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLE 105
            ::||..|:..|:     |...::|.:|||.|.|||:..|::|...|.||:|:|..:.....|.:|
  Fly   152 KESVKMTSEDLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKME 216

  Fly   106 YRFYKLLGSHADNAPDGIPRIYHLGTCG--GRYNAMVLELLGLSLEDLFNICAR-KFSLKTVLMI 167
            ....|.|        .|...:.....||  .|:|.:|::|.|.:|.:|.....| .|||.|.|.:
  Fly   217 VAVLKKL--------QGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRL 273

  Fly   168 AKQLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHK 232
            ..|:|..||.:||...::||:||.||.:||......: ::::|||||::|.........| |...
  Fly   274 GLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRR-VYMLDFGLARQYTTGTGEVRCP-RAAA 336

  Fly   233 SLTGTARYMSINTHMGREQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATP 297
            ...||.||.|||.|..||..|.|||.:|.:|.:.|:.|.|||:.:|..      :::|.||....
  Fly   337 GFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDK------EQVGLTKEKYD 395

  Fly   298 IEVLCDGHPEEFATYLRYVRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDWTGKTMSTPVGS 362
            ..:|....|.:...:|.:::.|.:.:.|||..|..||:....|:|..:...:||. |..||.:|:
  Fly   396 HRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWE-KVDSTAIGN 459

  Fly   363 LQ-TGHEVIISPNKDRH-NVT----AKTNAKGG--------------VAAWP------------- 394
            :. ||:..|...:...| |:|    |.:||.|.              .|..|
  Fly   460 ISATGNPSIPIKSDYMHGNITQMTVAASNASGTEYIRKRAEIETAHITATDPLNIKEKVDKNCNA 524

  Fly   395 -DVPKPGATLGNLTPADRHGSV---QVVSS---------TNGELNPDDPTAGHSNTP-------- 438
             .:.:|..  |:..|..:||:.   |.::|         ||.::    ..|...:.|
  Fly   525 TSLAQPAK--GSGEPMVQHGNAANNQNITSKGLQQQSTLTNSQV----AIANIQSAPSMIEREDV 583

  Fly   439 -------------ITQQP--EVEVVDETKCCCFFKRKKKKS----TRQKXLDGVQ---------- 474
                         ||.:|  |.:.|| ....|.|::|..::    ..:..|.||:
  Fly   584 QYTKLEEGAPTKFITMKPNGECDNVD-IAAKCIFEQKHVEANDDIVGRASLSGVEQHYKSQIKKH 647

  Fly   475 CSPEREAVTLLRATSHSNSRDSVLNNPSQDYIQQATSQHTLRYPP 519
            .|||.....:.|..:.:|.:.|.:|..:::..........|..||
  Fly   648 NSPEIANKQIQRTGTVTNDKTSEVNRSTEEQKSTFGRLRVLTAPP 692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	96/295 (33%)
		CK1gamma_C	354..439	CDD:463640	27/151 (18%)
Asator	NP_651924.2	STKc_TTBK	172..433	CDD:270919	91/276 (33%)