Protein Alignment gish and CG12147

DIOPT Version :10

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_649536.1
• Gene: CG12147 / 40651
• FlyBaseID: FBgn0037325
• Length: 477
• Species: Drosophila melanogaster
• Alignment Length: 457
• Identity: 172/457 - (37%)
• Similarity: 244/457 - (53%)
• Gaps: 71/457 - (15%)

  Fly    56 LMVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAP 120
            ::|...:|:.|:||.|:||||...:.|..:|.||||:|....|.|.|..|.|.|.:|....
  Fly    62 IIVAGKYRLLKRIGNGSFGELFQAEGLKYHEKVAIKLESSTVKHPLLPREARIYGILQGGL---- 122

  Fly   121 DGIPRIYHLGTCGGRYNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIY 185
             |||.:.|..| .|.||.||::|||.:||||.|:|:|.||:||.||:|.|:|.|:|.:|.|..|:
  Fly   123 -GIPHVKHYAT-EGAYNVMVMDLLGPTLEDLLNLCSRSFSMKTTLMLADQILARVELLHRRCFIH 185

  Fly   186 RDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGRE 250
            ||:||:|||:|  ..:.:..:::|||||||::..|.|.:||.|.|::.|.|||||.|:..|.. |
  Fly   186 RDIKPDNFLMG--LNRHQTQVYMIDFGLAKKFYSLRTQKHIGYTENRDLVGTARYASVRAHYA-E 247

  Fly   251 QSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRY 315
            ||||||||::|::.:||.||.|||||::|.:..::|:||.:.|...|::.||.|.|.||..||:|
  Fly   248 QSRRDDLESVGYLLLYFQRGRLPWQGIRAQSQAQKYEKIAEYKANIPLQQLCSGLPVEFFMYLKY 312

  Fly   316 VRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDWTG-KTMSTPVGSLQTGHE--------VII 371
            .|:|.|.|.|||.:|::||:.||..:....:..|||.. |..|....|.|.|.|        |::
  Fly   313 CRKLHFAEKPDYVYLQQLFKVLFRNQYKVCDFLFDWVVLKRESPEQQSQQKGRERDRGGKRNVVV 377

  Fly   372 SP----NKDRHNVTAKTNAKGGVAAWPDVPKPGATLGNLTPADRHGSVQVVSSTNGE-LNPDDPT 431
            ..    ||||.:.|.:...|.|              |:|...:.:      .||.|| .|.|.|.
  Fly   378 QKERHRNKDRDSDTQRCRIKNG--------------GDLLEIEEN------ESTTGEDPNEDKPQ 422

  Fly   432 AGHSNTPITQQPEVEVVDETKCCCFFKRKKKK----------STRQKXLDGVQCSPEREAVTLLR 486
            ..|...               |.|.:..:||:          .|.::.|.|.|   |:|....||
  Fly   423 KKHGKA---------------CSCSYHLQKKRLQDRDRRAPLMTERRILSGEQ---EQELELELR 469

  Fly   487 AT 488
            .:
  Fly   470 GS 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	135/293 (46%)
		CK1gamma_C	354..439	CDD:463640	24/97 (25%)
CG12147	NP_649536.1	STKc_CK1	67..331	CDD:270918	128/272 (47%)