Protein Alignment gish and CG8878

DIOPT Version :9

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001260913.1
• Gene: CG8878 / 36302
• FlyBaseID: FBgn0027504
• Length: 1004
• Species: Drosophila melanogaster
• Alignment Length: 885
• Identity: 144/885 - (16%)
• Similarity: 239/885 - (27%)
• Gaps: 424/885 - (47%)

  Fly     2 QRRERQASGGGPQT--------------TTAGPSAGNVANATTAL------------AGGKSSSN 40
            ::|:| .|||....              ::||.:||..|:..|.|            |...|..|
  Fly    28 EKRQR-LSGGSSSANGFEFHENDDEESCSSAGSAAGTEADPPTLLHTPQARSLLLTGASIASDHN 91

  Fly    41 N---------MYSTRQSVSTTTGVL--MVGPNFRVGKKIGCGNFGELRLGKN------LYNNEHV 88
            |         :|:.|.||...| :|  ::...:|:|:.||.|||||:.|..:      .......
  Fly    92 NSSVMESPRPVYTLRPSVVNGT-ILRDVLSKAWRLGRPIGKGNFGEIFLASDDTVCPASSETAKY 155

  Fly    89 AIKMEPMKS-----------------------------KAPQLHLEYRFYKLLGSHADNAPDGIP 124
            .:|:||..:                             .|||.|:..|          ..|.|||
  Fly   156 VVKIEPHSNGPLFVEIHCLINTSRNNDLSDAAEDAASLPAPQTHVLSR----------GPPSGIP 210

  Fly   125 RIYHLGT--CGG-RYNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIYR 186
            .....||  .|. ||..:||......|..|  |...:...|::|::|..:::.:|.:|.:...:.
  Fly   211 SFIASGTHYFGDVRYRFLVLPRFDRDLHSL--IKNSRVQQKSLLVLAVHIINVLENLHDKGYCHN 273

  Fly   187 DVKPENFLI-------------------------------------------------------- 195
            |:|.:|.::
  Fly   274 DIKAQNLMVSKCKYLRRQVVPKGNGYEDHYEEKQQTTDSGNSSEQETNDDDYFLKSEKFALKKIV 338

  Fly   196 ---------------GRTS---------------------------------------------- 199
                           |.||
  Fly   339 DIKQDEDEDDEDFDDGATSNSNNSNSLDVFHTPVNKKRSARNAIQFSGSNPVRACRREKRNSMYE 403

  Fly   200 ----------TKR---------------------------------------------------- 202
                      |||
  Fly   404 EMVKSHYLRPTKRISYREEFNEDGYPKETAENSDESPESSDNESDEFIPPSSRRSVIKRGRSAQI 468

  Fly   203 ---------------EKI----------------------------------IHIIDFGLAKEYI 218
                           ||:                                  :.:||||||.::.
  Fly   469 ATPKKTPVSTRASRQEKVKKEPNGDQKLRSRGSKHLDNNPTEYKFLPTEEEHVFLIDFGLASKFQ 533

  Fly   219 DLDTNRHIPYREHKSLTGTARYMSINTHMGREQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLK 283
            |...:|.....:.::..||..:.|.:.|:| ..|||.|||.||:..:|:..|.|||:.:.....:
  Fly   534 DRGVHRPFIMDQRRAHDGTLEFTSRDAHLG-AHSRRSDLECLGYNLLYWSEGYLPWKDVAQQQQQ 597

  Fly   284 ERYQKIGDTKRATPIEVLCDGH----PEEFATYLRYVRRLDFFETPDYDFLRRLFQDLFDRKGYT 344
            |:..:..:.......|:|...:    |:....:|..:.:|.:.|.|:|:..|::|:..:.|.||.
  Fly   598 EKVHRAKELFMTDVPEMLRQFYGKQVPKYLGEFLLQIGQLAYQERPNYERYRKIFKREYQRLGYD 662

  Fly   345 D---------------------EGE----FDWTGK---------TMSTPVGSLQTGHEVI--ISP 373
            .                     :|.    |:...|         |:|||...    |.:.  :||
  Fly   663 PCQMRLSSEEILRTCVSTKDVVDGSKCDIFELNNKAAVNVMRNSTLSTPFQE----HSLTNRVSP 723

  Fly   374 NKDRHNVTAKTNAKGGVAAWPDV-----------------------------------PKPGATL 403
            ...|.....||..|  ..:|.:|                                   .||...:
  Fly   724 KNLRSKSNKKTTKK--KFSWAEVLSQDPDQIARERAVKEFEREETICPLESRLPRRYEGKPTYAI 786

  Fly   404 GNLTPADRHGSVQV---VSSTNGELNPDDPTAGHSNTPITQQPEVEVVDETKCCCFFKRKKKKST 465
            .::....|...:.|   :.....:.:.||.........|.|:.:.|..|..         :.:..
  Fly   787 LDMEQRRREKGLVVQEHIEEEEEDADEDDEEENQEAMDIDQEEDGEAADSA---------EGEDE 842

  Fly   466 RQKXLDGVQCS-------------PEREAVTLLRATSHSN 492
            ..:.::|..||             ..|:..|..:|..|.|
  Fly   843 SDRSMEGSDCSDHSQKRARGRPKGTSRKQTTSRQAQPHQN 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	90/587 (15%)
		S_TKc	62..335	CDD:214567	84/542 (15%)
		CK1gamma_C	354..428	CDD:289378	18/122 (15%)
CG8878	NP_001260913.1	PKc_like	112..>286	CDD:304357	42/186 (23%)
		SPS1	123..>284	CDD:223589	40/172 (23%)
		SPS1	<491..756	CDD:223589	56/271 (21%)
		PKc_like	<517..652	CDD:304357	36/135 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11909
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910