Protein Alignment gish and Vrk2

DIOPT Version :9

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: XP_008768654.1
• Gene: Vrk2 / 360991
• RGDID: 1311585
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 426
• Identity: 115/426 - (26%)
• Similarity: 167/426 - (39%)
• Gaps: 98/426 - (23%)

  Fly    57 MVGPNFRVGKKIGCGNFGELRL----GKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSH-- 115
            |.|..:.:||.||.|.||.:.|    .|...:..|| ||:| .:...| |..|.:||:.....
  Rat    24 MEGNQWALGKMIGSGGFGLIYLAFPTNKPEKDARHV-IKVE-YQENGP-LFSELKFYQRAAKREC 85

  Fly   116 -----ADNAPD--GIPRIYHLGTC---GGRYNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQ 170
                 .....|  |:|..|..|..   |..|..||:|.||:.|:.|.|... .|...|||.:..:
  Rat    86 IQKWVKQRKLDYLGVPVFYGFGLTDFKGRSYRFMVMERLGIDLQKLLNQNG-AFKKLTVLQLGIR 149

  Fly   171 LLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYRE--HKS 233
            :|..:||:|....::.|:|..|.|:|..:..|   :::.|:||:..|  .....|..|.|  .|.
  Rat   150 MLDVLEYIHENEYVHGDIKAANLLLGYANPDR---VYLADYGLSYRY--CPNGNHKQYHEDPRKG 209

  Fly   234 LTGTARYMSINTHMGREQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPI 298
            ..||..:.|::.|.|...|||.|:|.||:..:.:|.|.|||                :|....|:
  Rat   210 HNGTLEFTSLDAHKGVAPSRRSDVEILGYCMLRWLCGKLPW----------------ETNLENPV 258

  Fly   299 EV------LCDGHPE-------------EFATYLRYVRRLDFFETPDYDFLRRLFQDLFDRKGYT 344
            .|      |.|..||             |.|.:..||..|.:...|||..|:::.     .....
  Rat   259 AVQTAKTKLLDELPESVLKWTTSGSSCRELAEFFMYVHNLAYDAKPDYQKLKKIL-----NPDGV 318

  Fly   345 DEGEFDWT----GKTMSTPVGSLQTGHEVIIS-----------PNKDRHNVTAKTNAKGGVAAW- 393
            ..|..|::    |..|.||:      |..:.|           |.|....|..:|.     |.|
  Rat   319 PLGPLDFSTKAQGVNMQTPI------HRKVDSPKAIKKPANEFPTKYTRKVCGETR-----ATWR 372

  Fly   394 --PDVPKPGATLGNL-TPAD-RHGSVQVVSSTNGEL 425
              .:..:|...|.:| ||.: |...|:..|.|..|:
  Rat   373 EEQEERRPAVLLSDLATPENSRTRKVREYSDTFSEM 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	91/333 (27%)
		S_TKc	62..335	CDD:214567	89/309 (29%)
		CK1gamma_C	354..428	CDD:289378	21/88 (24%)
Vrk2	XP_008768654.1	PKc_like	16..314	CDD:304357	91/319 (29%)
		Pkinase	29..290	CDD:278497	81/285 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810