Protein Alignment gish and cki1

DIOPT Version :9

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001342877.1
• Gene: cki1 / 2539610
• PomBaseID: SPBC1347.06c
• Length: 446
• Species: Schizosaccharomyces pombe
• Alignment Length: 479
• Identity: 208/479 - (43%)
• Similarity: 285/479 - (59%)
• Gaps: 85/479 - (17%)

  Fly    57 MVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAPD 121
            :||.:::||::||.|:||.:..|.||.||:.||||.||.:|.||||..|||.||||....
pombe     7 VVGVHYKVGRRIGEGSFGVIFEGTNLLNNQQVAIKFEPRRSDAPQLRDEYRTYKLLAGCT----- 66

  Fly   122 GIPRIYHLGTCGGRYNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIYR 186
            |||.:|:.|. .|.:|.:|::|||.|||||.::|.||||:|||.|.|||:|.|::.:|.:.|:||
pombe    67 GIPNVYYFGQ-EGLHNILVIDLLGPSLEDLLDLCGRKFSVKTVAMAAKQMLARVQSIHEKSLVYR 130

  Fly   187 DVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQ 251
            |:||:||||||.::|...:|:::|||:.|.|.|..|.:||||||.|:|:|||||||||||:||||
pombe   131 DIKPDNFLIGRPNSKNANMIYVVDFGMVKFYRDPVTKQHIPYREKKNLSGTARYMSINTHLGREQ 195

  Fly   252 SRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRYV 316
            |||||||||||:||||||||||||||||.|.|::|::||:.|::||:..||.|.||||..|:.|.
pombe   196 SRRDDLEALGHVFMYFLRGSLPWQGLKAATNKQKYERIGEKKQSTPLRELCAGFPEEFYKYMHYA 260

  Fly   317 RRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDW----TGKTMSTPVGSLQTGHEVIISPNKDR 377
            |.|.|..|||||:|:.||..:.:|...|::..|||    .||           |.:.:.|.|.:.
pombe   261 RNLAFDATPDYDYLQGLFSKVLERLNTTEDENFDWNLLNNGK-----------GWQSLKSRNAET 314

  Fly   378 HNVTAKTNAKGGVAAWPDVPKPGATLGNLTPA-DRHGSVQ-VVS-----------------STNG 423
            .|   :.::|      |..||    |.:.:|| ..|.|.| |||                 |.:.
pombe   315 EN---QRSSK------PPAPK----LESKSPALQNHASTQNVVSKRSDYEKPFAEPHLNSASDSA 366

  Fly   424 ELN----PDDPTAGHSNTPI-------TQQP-EVEVVDETKCCCFFKRKKKKSTRQKXLDGVQCS 476
            |.|    |:.||...:.|.:       |.|| .|:|.|.:         :::.||:: .:..:
pombe   367 EPNQNSLPNPPTETKATTTVPDRSGLATNQPAPVDVHDSS---------EERVTREQVQNATK-- 420

  Fly   477 PEREA--------VTLLRATSHSN 492
             |.||        .::|...|.||
pombe   421 -ETEAPKKKKSFWASILSCCSGSN 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	165/296 (56%)
		S_TKc	62..335	CDD:214567	159/272 (58%)
		CK1gamma_C	354..428	CDD:289378	21/96 (22%)
cki1	NP_001342877.1	STKc_CK1_fungal	11..287	CDD:271029	161/281 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	274	1.000	Domainoid score	I318
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	357	1.000	Inparanoid score	I469
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001189
OrthoInspector	1	1.000	-	-		otm47397
orthoMCL	1	0.900	-	-		OOG6_101750
Panther	1	1.100	-	-	LDO	PTHR11909
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X651
TreeFam	0	0.000	Not matched by this tool.
	10	9.860