DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment gish and ZC581.2

DIOPT Version :9

Sequence 1:NP_001262624.1 Gene:gish / 49701 FlyBaseID:FBgn0250823 Length:537 Species:Drosophila melanogaster
Sequence 2:NP_491912.3 Gene:ZC581.2 / 191200 WormBaseID:WBGene00022632 Length:342 Species:Caenorhabditis elegans


Alignment Length:297 Identity:82/297 - (27%)
Similarity:139/297 - (46%) Gaps:25/297 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    62 FRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKA---PQLHLEYR-FYKLLGSHADNAPDG 122
            |.|...||.|.||::..|.:....|.|.||:||:..|.   .::.||.: .|:|         .|
 Worm    48 FMVKGLIGRGGFGQIYYGSDATFPEDVVIKIEPVVLKGRPRRRMILEQKVLYRL---------QG 103

  Fly   123 IPRIYHLGTCG--GRYNAMVLELLGLSLEDLFNIC-ARKFSLKTVLMIAKQLLHRIEYVHSRHLI 184
            .|.:..:...|  .:.|.:|::|||.::.||.... .::.|..||..|..|.:..:..|||...|
 Worm   104 RPHVPIMCASGHTEQLNFIVMQLLGPNIGDLKKRSPVKRLSQTTVARIMIQGIAALRDVHSLGYI 168

  Fly   185 YRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGR 249
            :|||||.|...|.|.:.|. ::.::|:|:.:.:.::|..|. ..|......||.||.|:..|.|:
 Worm   169 HRDVKPANMCFGVTQSTRH-VLKLVDYGMVRRFKNVDGTRR-KQRYKPGFRGTLRYSSVRVHDGK 231

  Fly   250 EQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLR 314
            ||:..||..::.:.....|..:|||:.:..|.:  |..|:......:|..:|...:   |:.:..
 Worm   232 EQTPVDDFVSMAYSGAELLLVNLPWKLVSTDDI--RQTKVDFNTPNSPYLLLTGPY---FSVFCG 291

  Fly   315 YVRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDW 351
            .:..|...:.||:..|:.|..|:  .:|.:....:||
 Worm   292 AIFNLRSEDEPDHSSLQNLLCDM--TRGKSLREAYDW 326

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
gishNP_001262624.1 STKc_CK1_gamma 61..354 CDD:271028 82/297 (28%)
S_TKc 62..335 CDD:214567 78/279 (28%)
CK1gamma_C 354..428 CDD:289378
ZC581.2NP_491912.3 PKc_like 47..311 CDD:389743 77/278 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1164
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.