Protein Alignment gish and Y47G6A.13

DIOPT Version :10

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_491162.1
• Gene: Y47G6A.13 / 189993
• WormBaseID: WBGene00021639
• Length: 468
• Species: Caenorhabditis elegans
• Alignment Length: 308
• Identity: 77/308 - (25%)
• Similarity: 131/308 - (42%)
• Gaps: 13/308 - (4%)

  Fly   136 YNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIYRDVKPENFLIGRTST 200
            |..||..|.|..|..|.....|.|:..|.:.:|...|:.::.:|....::|||||.|.:......
 Worm    95 YRYMVTTLCGKDLMALRMKIQRGFNDATAMRVAVFTLYGLKQLHEAGYVHRDVKPGNIMTAANKG 159

  Fly   201 KREKIIHIIDFGLAKEYI---DLDTNRHIPYREHKSLTGTARYMSINTHMGREQSRRDDLEALGH 262
            :..:::.:||||:|:.::   |....:..|.|....|.||.||.|:|.|..:||.|.|||.|:.:
 Worm   160 RDARVMLLIDFGMARTFVMAGDDGKKKLRPMRRRIPLRGTIRYCSMNVHERKEQGRCDDLVAMIY 224

  Fly   263 MFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRYVRRLDFFETPDY 327
            ..:|...| |||..||.:      ::|...|::|....|.:..|:|..:...|:|.|.:.:.|:|
 Worm   225 SIVYLTLG-LPWSNLKDE------KEIMSMKKSTKDLALFEDLPDELKSIFEYLRTLSYADRPNY 282

  Fly   328 DFLRRLFQDLFDRKGYTDEGEFDWTGKTMSTPVGSLQTGHEVIISPNKDRHNVTAKTNAKGGVAA 392
            :.:..|......|........::|....|.....:.:...|......|::.|   |.|.....:.
 Worm   283 EKIYNLLMAAITRLKINFLDPYEWEDDEMERMAKAEKEEKEKEEKEKKEKEN---KENELSADSM 344

  Fly   393 WPDVPKPGATLGNLTPADRHGSVQVVSSTNGELNPDDPTAGHSNTPIT 440
            ...:|...|...:....:.....:|..:::||...|.......|..|:
 Worm   345 KTAIPAKSAKAESEVAGEVDEQKKVKDNSSGEQQQDTLNVDKGNKLIS 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	63/220 (29%)
		CK1gamma_C	354..439	CDD:463640	13/84 (15%)
Y47G6A.13	NP_491162.1	Protein Kinases, catalytic domain	24..289	CDD:473864	60/200 (30%)