Protein Alignment gish and T15B12.2

DIOPT Version :9

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001367879.1
• Gene: T15B12.2 / 188528
• WormBaseID: WBGene00020531
• Length: 446
• Species: Caenorhabditis elegans
• Alignment Length: 422
• Identity: 100/422 - (23%)
• Similarity: 171/422 - (40%)
• Gaps: 85/422 - (20%)

  Fly     2 QRRERQASGGGPQTTTAGPSAGNVANATTALAGGKSS------SNNMYSTRQSVSTTTGVLMVGP 60
            ||.|::|.....||.:..|             |.|..      |||   |:...:.|..|..|..
 Worm     7 QRTEKEAVTKDGQTGSKKP-------------GYKKKPVKKLLSNN---TKVKTNKTKRVWCVQA 55

  Fly    61 NFRVGKKIGCGNFGELRLGKNLYNNEH----VAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAPD 121
            :      ||.|.||::   ..:|:..:    .|:|.|...::..:|.:|....|.:.::....
 Worm    56 H------IGSGGFGDV---YRVYDEPNPKMEYAMKTEVHGAQQRRLSIEKSILKEIDTYTTTH-- 109

  Fly   122 GIPRIYHLGTC----GGR---YNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVH 179
              .:..|.  |    .|:   |:.:|:.|:|.|||.:..:..|:::...|:.:|.|:|..:|.:|
 Worm   110 --KKSRHF--CELIDSGQTKDYSWIVMTLIGPSLESVRRMLKRQYTKSCVINMALQILDAVEVMH 170

  Fly   180 SRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHI-PYREHKSLTGTARYMSI 243
            ....|:||:||.|...| |..:.:.:::::|||:::..........: ..||.....||.::.|.
 Worm   171 EVGFIHRDLKPANICTG-TPPQDDHVLYVLDFGISRRVFKSSKCHELRNKRERVPFFGTRKFSSR 234

  Fly   244 NTHMGREQSRRDDLEALGHMFMYFL-------RGSLPWQGLKADTLKERYQKIGDTKRA---TPI 298
            ..|..::|.|:||:|.    ::|.:       || |.|....||.     .||.:.|.|   .|.
 Worm   235 ACHQEKDQGRKDDMET----YLYTILDLFHNERG-LSWSKDLADV-----NKIIEKKHALFENPT 289

  Fly   299 EVLCDGHPEEFATYLRYVRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGE--FDWTG-------- 353
            :.|....|......:.|:|.|.|.:..||..:....:....:...:|..:  .||||
 Worm   290 KELDKIIPSGIDNIIVYLRGLKFEDPVDYRQIENELRTAGKKMAPSDSSDETMDWTGKLEQLLKE 354

  Fly   354 ----KTMSTPVGSLQTGHEVIISPNKDRHNVT 381
                |.:.||.|.....:| .:...:||...|
 Worm   355 ANKNKAVGTPKGEETLLYE-RLKAKRDRDMTT 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	76/328 (23%)
		S_TKc	62..335	CDD:214567	71/294 (24%)
		CK1gamma_C	354..428	CDD:289378	8/28 (29%)
T15B12.2	NP_001367879.1	STKc_TTBK	51..353	CDD:270919	77/327 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810