DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gish and K08H2.5

DIOPT Version :9

Sequence 1:	NP_001262624.1	Gene:	gish / 49701	FlyBaseID:	FBgn0250823	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001361832.1	Gene:	K08H2.5 / 187176	WormBaseID:	WBGene00010692	Length:	304	Species:	Caenorhabditis elegans

Alignment Length:	289	Identity:	63/289 - (21%)
Similarity:	109/289 - (37%)	Gaps:	69/289 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 NFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLH---------LEYRFYKLLGSHA 116
            |:::.:.:|.|.:|......:. ::.|..:.:     ||..|.         ||....:.:.:..
Worm    12 NYKIVEVLGSGEYGTAFACVDA-DSRHSTLAL-----KASNLETIFCENCFKLERTVLQRISTLG 70

  Fly   117 DNAPDGIPRIYHLGTCGGRYNAMVLELLGLSLEDLFNICAR----KFSLKTVLMIAKQLLHRIEY 177
            .|.....|.:............:|:...|.||.|   :|.|    |||...||.|...:...::.
Worm    71 TNEKSRFPTLVDNFVVDSTLGCLVMTKEGDSLGD---VCKRNDPKKFSPTNVLKIMLSVGKSLQT 132

  Fly   178 VHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKE-------YIDLDTNRHIPYREHKSLT 235
            :||...|:||:...|.|..:|.|.... ..:||:|:.|:       |:.....|.:.::|
Worm   133 IHSLGYIHRDIHWNNVLFAKTITPASP-CKLIDYGVGKKFRNRRGNYVKNRPQRDVNFKE----- 191

  Fly   236 GTARYMSINTHMGREQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKE---------RYQKI-- 289
              ..::|.|..||...:.:||..:|  ||:          |||...:..         |:||:
Worm   192 --CGHVSWNVMMGGVPNLKDDFSSL--MFL----------GLKISGISSLEIGSVSEVRHQKMIF 242

  Fly   290 ----GDTKRATP--IEVLC---DGHPEEF 309
                ....|:.|  ::|.|   |...|:|
Worm   243 ELDPSRFLRSVPWLLKVACVIVDSDAEKF 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	63/289 (22%)
		S_TKc	62..335	CDD:214567	62/288 (22%)
		CK1gamma_C	354..428	CDD:289378
K08H2.5	NP_001361832.1	PKc_like	12..>185	CDD:389743	39/182 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160806
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830