Protein Alignment gish and F41G3.5

DIOPT Version :10

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_495378.2
• Gene: F41G3.5 / 185631
• WormBaseID: WBGene00018301
• Length: 331
• Species: Caenorhabditis elegans
• Alignment Length: 326
• Identity: 93/326 - (28%)
• Similarity: 159/326 - (48%)
• Gaps: 35/326 - (10%)

  Fly    36 KSSSNNMYSTRQSVSTTTGVLMVGPNFRVGKKIGCGNFGELRLGKNLYNNEHV-----AIKMEPM 95
            |.:|.|..|  :.|....|..::  :::|.:.|..|.||.      :|..:|:     |:|:|..
 Worm     6 KENSENQVS--EGVELDKGYRLL--DYKVVRFIAKGAFGA------VYQVDHINTLPFALKLESR 60

  Fly    96 KSKAPQLHLEYRFYKLLGSHADNAPDGIPRIYHLGTCG--GRYNAMVLELLGLSLEDLFNICA-R 157
            .|:...|.:|....:.|      .|...|....:..||  .::|.:::.|:|.:|.:|...|. |
 Worm    61 SSETRNLKMEAVVLRSL------LPIRSPYFCRVFFCGKAEKFNFLIMTLVGKNLSELRANCPNR 119

  Fly   158 KFSLKTVLMIAKQLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYI-DLD 221
            |||.:|.|.|..|:::.|:.:||...|:||:||.||.|...:..:   :.::|||:.::|: |..
 Worm   120 KFSRRTGLQIGIQMINAIQQLHSIGFIHRDIKPANFCINLDNPHQ---LVMVDFGMCRKYLNDGG 181

  Fly   222 TN-RHIPYREHKSLTGTARYMSINTHMGREQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKER 285
            |. ||..:..| ...||.||..:.||.||:..|::|||.:.::.:..|.|:|||..::.....|.
 Worm   182 TQLRHPRWSVH-GFRGTVRYAPLATHYGRDSCRKEDLETIFYVLVELLVGTLPWMTMEEHIHVEH 245

  Fly   286 YQKIGDTKRATPIEVLCDGHPEEFATYLRYVRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFD 350
            .:::.   |.|.:.....|.|::....|.|:..|.|::.|||..:|.|..  |..:.....|.|:
 Worm   246 SKQVA---RTTGLREFLSGCPKQLVHILLYIDNLRFYDAPDYALIRGLLS--FALENCQHNGSFE 305

  Fly   351 W 351
            |
 Worm   306 W 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	87/301 (29%)
		CK1gamma_C	354..439	CDD:463640
F41G3.5	NP_495378.2	Protein Kinases, catalytic domain	28..292	CDD:473864	83/282 (29%)