DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gish and F39F10.2

DIOPT Version :9

Sequence 1:	NP_001262624.1	Gene:	gish / 49701	FlyBaseID:	FBgn0250823	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_510731.1	Gene:	F39F10.2 / 185497	WormBaseID:	WBGene00018202	Length:	298	Species:	Caenorhabditis elegans

Alignment Length:	340	Identity:	73/340 - (21%)
Similarity:	137/340 - (40%)	Gaps:	104/340 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 STRQSVSTTTGVLMVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRF 108
            ||.|.:.          |:.:||.:|.|:||.::|.::..:|                   |.|.
Worm     2 STMQQIG----------NYTLGKVLGRGSFGSVQLAQDKRSN-------------------EMRV 37

  Fly   109 YKLLGSHADNAPD-----------------GIPRIYHLGTCGGRYNAMVLELLGLSLEDLFNICA 156
            .||:....|...|                 |:.:::..|:. ..:|.:|:|.|.   :||..|..
Worm    38 MKLIRKERDGHRDETWRRETFTLTALSDVSGVTKMFEYGST-ETHNWIVMEQLS---DDLITIVR 98

  Fly   157 RK----FSLKTVLMIAKQLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEY 217
            |.    ||..|...|..||:..::.:|:..:::.|:|.:|.::...:..|:.:  ::|:||:..:
Worm    99 RNETKMFSKPTSYQIMWQLVKILQDIHAIGIVHTDIKADNLMVSYKNRVRKLV--LVDYGLSCWF 161

  Fly   218 IDLDTNR-----------HIPYREHKSLTGTARYMSINTHMGREQSRRDDLEALG------HMFM 265
            .|.:.||           |:.:...|:.||       :.||..|     ||..:.      |.||
Worm   162 KDHNQNRTPPAPFDNRCMHLIHTPAKTATG-------HPHMEAE-----DLVQVAYLSCSLHQFM 214

  Fly   266 YFLRGSLPWQGLKA---DTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRYVRRLDFFETPDY 327
                   ||:.::|   ..:|:::.|       .|.:.|  |:.::....::.:.:......|||
Worm   215 -------PWKDVEAPKMTKMKKKFAK-------NPKKYL--GNHQDLKPIIKMLVKQKHGVEPDY 263

  Fly   328 DFLRRLFQDLFDRKG 342
            :.:..|.||:|...|
Worm   264 EGILDLLQDMFGSLG 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	70/323 (22%)
		S_TKc	62..335	CDD:214567	65/313 (21%)
		CK1gamma_C	354..428	CDD:289378
F39F10.2	NP_510731.1	PKc_like	9..271	CDD:389743	66/314 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160840
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830