Protein Alignment gish and F33D11.7

DIOPT Version :10

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_491697.1
• Gene: F33D11.7 / 185229
• WormBaseID: WBGene00018004
• Length: 347
• Species: Caenorhabditis elegans
• Alignment Length: 301
• Identity: 84/301 - (27%)
• Similarity: 143/301 - (47%)
• Gaps: 15/301 - (4%)

  Fly    58 VGPNFRVGKKIGCG-NFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAPD 121
            :|.|::|.|.|... .|..:.:.:::...:..|:|:| .|::|.:: |::..:.||.....|...
 Worm    38 IGKNWKVVKAIQSDKGFNTIYVAEHVQKKKLAAVKVE-RKTEAIKM-LQFELFVLLTVEKKNQCK 100

  Fly   122 GIPRIYHLGTCGGRYNAMVLELLGLSLEDL-FNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIY 185
            ...:::..|. ...||.:.:.|.|.||..| .|....|.::...|.:|:|.|..:|.:|....|:
 Worm   101 QFCKLFEKGN-EKEYNWIAITLCGKSLRALRKNQPKGKLTVACGLSVAQQCLKGLEELHRMGFIH 164

  Fly   186 RDVKPENFLIGRTSTKRE---KIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHM 247
            |:|.|..|.|||.:...:   :.|:|:|||.|.:|::.|.....|........|:.|:|......
 Worm   165 RNVAPSVFAIGRYTGDNQSDMRNIYILDFGFAHQYMNKDGTLKPPSAHPWKYVGSLRHMPRAAFS 229

  Fly   248 GREQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATY 312
            ..|.||.:|||...:|.:..::|.|||..||.......|||:  .:....:..:..|.|.||...
 Worm   230 KVEFSRMEDLEMWFYMSVELVKGCLPWAHLKKPKEVHDYQKL--CRNGLQMREMLGGLPPEFFDI 292

  Fly   313 LRYVRRLDFFETPDYDFLRRLFQD--LFDRKGYTDEGEFDW 351
            ::.|.:|.|.:||:|..:..|..:  ||..|   :|..:||
 Worm   293 MQMVDKLSFTDTPNYKEIYGLLTNAILFSGK---NEFPYDW 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	83/298 (28%)
		CK1gamma_C	354..439	CDD:463640
F33D11.7	NP_491697.1	STKc_TTBK	41..315	CDD:270919	77/278 (28%)