DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gish and F33D11.7

DIOPT Version :9

Sequence 1:	NP_001262624.1	Gene:	gish / 49701	FlyBaseID:	FBgn0250823	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_491697.1	Gene:	F33D11.7 / 185229	WormBaseID:	WBGene00018004	Length:	347	Species:	Caenorhabditis elegans

Alignment Length:	301	Identity:	84/301 - (27%)
Similarity:	143/301 - (47%)	Gaps:	15/301 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 VGPNFRVGKKIGCG-NFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAPD 121
            :|.|::|.|.|... .|..:.:.:::...:..|:|:| .|::|.:: |::..:.||.....|...
Worm    38 IGKNWKVVKAIQSDKGFNTIYVAEHVQKKKLAAVKVE-RKTEAIKM-LQFELFVLLTVEKKNQCK 100

  Fly   122 GIPRIYHLGTCGGRYNAMVLELLGLSLEDL-FNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIY 185
            ...:::..|. ...||.:.:.|.|.||..| .|....|.::...|.:|:|.|..:|.:|....|:
Worm   101 QFCKLFEKGN-EKEYNWIAITLCGKSLRALRKNQPKGKLTVACGLSVAQQCLKGLEELHRMGFIH 164

  Fly   186 RDVKPENFLIGRTSTKRE---KIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHM 247
            |:|.|..|.|||.:...:   :.|:|:|||.|.:|::.|.....|........|:.|:|......
Worm   165 RNVAPSVFAIGRYTGDNQSDMRNIYILDFGFAHQYMNKDGTLKPPSAHPWKYVGSLRHMPRAAFS 229

  Fly   248 GREQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATY 312
            ..|.||.:|||...:|.:..::|.|||..||.......|||:  .:....:..:..|.|.||...
Worm   230 KVEFSRMEDLEMWFYMSVELVKGCLPWAHLKKPKEVHDYQKL--CRNGLQMREMLGGLPPEFFDI 292

  Fly   313 LRYVRRLDFFETPDYDFLRRLFQD--LFDRKGYTDEGEFDW 351
            ::.|.:|.|.:||:|..:..|..:  ||..|   :|..:||
Worm   293 MQMVDKLSFTDTPNYKEIYGLLTNAILFSGK---NEFPYDW 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	83/298 (28%)
		S_TKc	62..335	CDD:214567	76/277 (27%)
		CK1gamma_C	354..428	CDD:289378
F33D11.7	NP_491697.1	STKc_TTBK	41..315	CDD:270919	77/278 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160843
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740