DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gish and C44C10.7

DIOPT Version :9

Sequence 1:	NP_001262624.1	Gene:	gish / 49701	FlyBaseID:	FBgn0250823	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_509953.1	Gene:	C44C10.7 / 183456	WormBaseID:	WBGene00008088	Length:	341	Species:	Caenorhabditis elegans

Alignment Length:	225	Identity:	50/225 - (22%)
Similarity:	84/225 - (37%)	Gaps:	56/225 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 NFRVGKKIGCGNFGEL--------RLG--------------KNLYNNEHVAIKMEPMKSKAPQLH 103
            |:.:...:|.|.||.:        ||.              :|.|..|.:.::.....|:..|.
Worm    50 NYEIISVLGGGAFGTVYSCVDVDDRLNQLAIKAMDLSTVTRENSYKLELMVLQRVETLSEVEQT- 113

  Fly   104 LEYRFYKLLGSHADNAPDGIPRIYHLGTCGGRYNAMVLELLGLSLEDLF--NICARKFSLKTVLM 166
               ||.||:|:...::..|...::..|.|               :::::  |...| ||...||.
Worm   114 ---RFSKLIGNFIQDSSLGFFVMHKEGEC---------------VDEVWMRNKSGR-FSASNVLK 159

  Fly   167 IAKQLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRH-----I 226
            |...:.|.:..:|....|:||....|.|.....|.... :.|:|||:.:.:    .||.     .
Worm   160 IVHCMAHGLRSLHKIGFIHRDCHAGNILFASRLTPTAP-VKIVDFGIGRRF----ANRRGHPIPS 219

  Fly   227 PYREHKSLTGTARYMSINTHMGREQSRRDD 256
            |.|:...|  ...:.|:|.|:|.....:||
Worm   220 PSRDIDFL--GCEHCSVNVHVGGIPGPKDD 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	50/225 (22%)
		S_TKc	62..335	CDD:214567	49/224 (22%)
		CK1gamma_C	354..428	CDD:289378
C44C10.7	NP_509953.1	PKc_like	50..>250	CDD:389743	50/225 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160804
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830