DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gish and C25H3.1

DIOPT Version :9

Sequence 1:	NP_001262624.1	Gene:	gish / 49701	FlyBaseID:	FBgn0250823	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001379695.1	Gene:	C25H3.1 / 182922	WormBaseID:	WBGene00016111	Length:	211	Species:	Caenorhabditis elegans

Alignment Length:	207	Identity:	53/207 - (25%)
Similarity:	106/207 - (51%)	Gaps:	23/207 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 FRVGKKIGCGNFG------ELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAP 120
            ::|.|.:|.|::|      ||:.|      :..|:|.|....|.|.|..|.:..|.:.:.:.
Worm    19 YKVTKLLGGGSYGCVHEVIELKTG------DRYAMKSEYSSMKKPILLNELKVMKAIYTFSS--- 74

  Fly   121 DGIPRIYHLGTCGGRYNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIY 185
            ..:.::..:|..|.. ..:::::|..:::::|.:.....:|.|.:..:.|.|..:|::|....::
Worm    75 QHVLKVRDMGVHGST-KFIIMQMLEKNMDEVFELLGGSMTLNTAVATSYQCLEGLEFMHWAGFLH 138

  Fly   186 RDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLT---GTARYMSINTHM 247
            ||:||.|:.:...|.:..:.|:|||:|:.|.::|   |.:: .|:.:.:|   ||..:..|.:|.
Worm   139 RDIKPNNYCLDANSGQGLRTIYIIDYGICKRFVD---NNNV-IRQPRKITKFRGTLDFAPIVSHE 199

  Fly   248 GREQSRRDDLEA 259
            .||.||..|||:
Worm   200 LREHSRGSDLES 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	53/207 (26%)
		S_TKc	62..335	CDD:214567	53/207 (26%)
		CK1gamma_C	354..428	CDD:289378
C25H3.1	NP_001379695.1	PKc_like	18..>211	CDD:419665	52/205 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160792
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740