Protein Alignment gish and C38C3.4

DIOPT Version :10

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001023703.2
• Gene: C38C3.4 / 178641
• WormBaseID: WBGene00016513
• Length: 330
• Species: Caenorhabditis elegans
• Alignment Length: 317
• Identity: 85/317 - (26%)
• Similarity: 136/317 - (42%)
• Gaps: 52/317 - (16%)

  Fly    62 FRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAPDGIPRI 126
            :.||||:..|.:|.:.......:.:..|.|:|..::.:..|..:   |.::...|....:.:.|:
 Worm    36 YAVGKKVAQGRYGAVYEVLRRSDGKPFACKLEICEAHSHGLDQD---YSVMTKAAKRGAENLVRM 97

  Fly   127 YHLGTCGGRYNAMVLELLGLSLEDL-FNICARKFSLKTVLMIAK------QLLHRIEYVHSRHLI 184
            ...|.....:..:::.|||.:|.:| |.....:|||.|.|.:|.      |.||::.|||
 Worm    98 IDRGKIEEHFKFIIMPLLGENLMNLRFLFEDGRFSLSTGLRLALFAIQPIQSLHQLGYVH----- 157

  Fly   185 YRDVKPENFLIGRTSTKREKIIH---------IIDFGLAKEYIDLDTNRHIPYREHKSLTGTARY 240
             ||:|..||.|.     ..:::|         :||:|:.:.:.|.......|..:.| ..||.||
 Worm   158 -RDIKASNFCIA-----DPQMLHQNPEALKLCLIDYGICRSFKDKSGELKTPRTDIK-FRGTNRY 215

  Fly   241 MSINTHMGREQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLC--- 302
            .|:..|.|.|||.:||:|:..:|.:..:.|:|||..:..|..||    :...|.|      |
 Worm   216 ASLAAHYGDEQSAKDDMESWFYMMIELISGNLPWSFMHRDQHKE----VASMKEA------CRTT 270

  Fly   303 DGH-------PE-EFATYLRYVRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDW 351
            ||.       |. ||.....|:..|.:..|.||.|:..:.|......|.....:|||
 Worm   271 DGSLIMMKFCPRVEFHRIQAYLMGLKYQNTVDYTFISEMVQLAMRNNGVRMNEKFDW 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	85/317 (27%)
		CK1gamma_C	354..439	CDD:463640
C38C3.4	NP_001023703.2	Protein Kinases, catalytic domain	36..308	CDD:473864	80/296 (27%)