DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gish and K09C6.8

DIOPT Version :9

Sequence 1:	NP_001262624.1	Gene:	gish / 49701	FlyBaseID:	FBgn0250823	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001343667.1	Gene:	K09C6.8 / 178590	WormBaseID:	WBGene00019562	Length:	551	Species:	Caenorhabditis elegans

Alignment Length:	354	Identity:	76/354 - (21%)
Similarity:	128/354 - (36%)	Gaps:	113/354 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 AGGKSSSNNM-YSTRQSVSTTTGVLMVGPNFR---VGKKIGCGNF---------GEL------RL 78
            |.||:....: |..:..|..|...:.:..||:   .|.|:..|||         |.:      .|
Worm    34 APGKTGWKRVTYENKFPVVQTLNSVEIESNFKHISKGTKVMLGNFPMTPKDDVIGNMGMVVCRYL 98

  Fly    79 GKNLYNNE------HVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAPDGIPRIYHLGTCGGRYN 137
            ..|.|:..      ..||..:...||..|:     ..||..:.:.||    .|:...|.......
Worm    99 ALNQYHQTIYHFHFRAAINFDSAGSKEAQI-----LSKLNMNRSHNA----MRVMRYGQYLNLQY 154

  Fly   138 AMVLEL---LGLSLE----DLFNICARKFSLKTVLMIAKQL-----LHRIEYVHSRHLIYRDVKP 190
            .:..||   ||..::    |||:         :|.:|.:..     ||:|.|.|      .|::|
Worm   155 ILTQELSSDLGFIVQNTTLDLFS---------SVHLIQQTFYCISDLHKIGYTH------LDIRP 204

  Fly   191 ENFLIGRTSTKREKIIHIIDFGLAKEYIDLDT----NRHIPYREHKSL-------TGTARYMS-- 242
            .:|.:.|.:    |.:.:::     .:.:.:|    :|:|...:|..|       ...||..|
Worm   205 SSFSLLRNN----KAVVVLN-----SFFNSETRQNISRNIRTTKHNGLQPLYVQQARHARNKSER 260

  Fly   243 -------INTHMGREQSRR------DDLEALGHM---FMYFLRGSLPW--QGLKAD------TLK 283
                   |||:|.|.|..|      ||.|:..::   |:..|...|.:  |..|.|      .::
Worm   261 EPLPKNVINTYMSRRQHFRLARGPADDYESWFYICARFITLLSSDLGFIVQNTKLDLYSAVHLIQ 325

  Fly   284 ERYQKIGDTKRA--TPIEVLCDGHPEEFA 310
            :.:..|.|..:.  |.:::    .|..|:
Worm   326 QTFYCISDLHKIGYTHLDI----RPSSFS 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	70/325 (22%)
		S_TKc	62..335	CDD:214567	69/324 (21%)
		CK1gamma_C	354..428	CDD:289378
K09C6.8	NP_001343667.1	SPS1	88..>222	CDD:223589	34/166 (20%)
		PKc_like	<179..>300	CDD:328722	31/135 (23%)
		PKc_like	<299..461	CDD:328722	10/56 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160776
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930