Protein Alignment gish and ttbk-4

DIOPT Version :10

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_501824.1
• Gene: ttbk-4 / 177871
• WormBaseID: WBGene00012169
• Length: 366
• Species: Caenorhabditis elegans
• Alignment Length: 316
• Identity: 93/316 - (29%)
• Similarity: 154/316 - (48%)
• Gaps: 48/316 - (15%)

  Fly    61 NFRVGKKIGCGNFGELRLGKNLYNNEHV--------------AIKMEPMKSKAPQLHLEYRFYKL 111
            ::::||.|..|.||::.:..::.:.:.|              |||:|.|               :
 Worm    23 DWKIGKTIDEGGFGKVYIATSISDPKKVAALKAESNEIEGGSAIKLEAM---------------I 72

  Fly   112 LGSHADNAPDGIPRIYHLGTCGGR--YNAMVLELLGLSLEDLFN---ICARKFSLKTVLMIAKQL 171
            |.....|.|  :|.|..:..|..|  |..||:.|||.:|..|.:   :....||..|...|..|.
 Worm    73 LNKLNANGP--VPHIPVVHLCAKRKLYCYMVMTLLGRNLRKLKSTNLVVNNGFSRGTWSRIGIQC 135

  Fly   172 LHRIEYVHSRHLIYRDVKPENFLIG-RTSTKREKIIHIIDFGLAKEY--IDLDTNRHIPYREH-- 231
            |:.::|||....|:|||||:|||:| .|.::|.:|:||:|||||:.:  .....|:.|..|..
 Worm   136 LYALKYVHDNGFIHRDVKPQNFLLGNETDSERARIVHILDFGLARPFAVFHARENKWIARRARGT 200

  Fly   232 KSLTGTARYMSINTHMGREQSRRDDLEALGHMFMYFLRG-SLPWQGLKADTLKERYQKIGDTKRA 295
            ....||.||.|.|.|:.:||.|.||:.:|.::.:....| :||||   .|:.:||.:::   |..
 Worm   201 AEFRGTLRYTSPNVHLRKEQGRVDDVWSLLYVIIELNGGKALPWQ---TDSQRERVEQM---KLN 259

  Fly   296 TPIEVLCDGHPEEFATYLRYVRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDW 351
            .|.:|:....|......:.::..||:::.|||..:.:.|..:.:.:..|...::||
 Worm   260 LPAKVVMSNMPACMDKVMPHLASLDYYQRPDYHMIFKCFWQVMENEKITPSSKYDW 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	93/316 (29%)
		CK1gamma_C	354..439	CDD:463640
ttbk-4	NP_501824.1	Protein Kinases, catalytic domain	24..298	CDD:473864	89/296 (30%)