Protein Alignment gish and C49C8.1

DIOPT Version :9

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_501483.2
• Gene: C49C8.1 / 177670
• WormBaseID: WBGene00016765
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 453
• Identity: 98/453 - (21%)
• Similarity: 157/453 - (34%)
• Gaps: 171/453 - (37%)

  Fly    61 NFRVGKKIGCGNFGEL-RLGKN--------LYNNEHV---AIKME-------PMKSKAPQLHLEY 106
            ::.:..||..|.||:: ::.|:        |.:|..|   |||:|       |..:..|:|
 Worm    26 DYEIVSKIDEGGFGQVFKVTKDHKTFYAMKLESNFQVGGSAIKLEINVLSQLPKNTVFPEL---- 86

  Fly   107 RFYKLLGSHADNAPDGIPRIYHLGTCGG---RYNAMVLELLGLSLEDLFNICARK-----FSLKT 163
                                    .|||   ||:.:||||||   ::|..:.|:.     ||..|
 Worm    87 ------------------------ICGGKRPRYHFLVLELLG---DNLKALKAQSPNPSVFSDGT 124

  Fly   164 VLMIAKQLLHRIEYVHSRHLIYRDVKPENFLIG--RTSTKREKIIHIIDFGLAKEYI-------- 218
            ...|..|.|:.::.:|....::||:||.||.||  ..|..|.:.:.:.|||||::::
 Worm   125 WSRIGIQCLYAMKMMHDSGFVHRDIKPSNFAIGYSTASESRSRRVLLFDFGLARKFVKKEKNLAP 189

  Fly   219 -------------------------DLDTNRHIPY------------------------------ 228
                                     ||...|..|.
 Worm   190 IVTKKESKISKSKTLPSKGPSTKSKDLKPGRSKPILNRKAEQMKIKKNFNMLIPPKSIDQSQRTA 254

  Fly   229 --------------REHKSLTGTARYMSINTHMGREQSRRDDLEALGHMFMYFLRGSLPWQGLKA 279
                          |.|....||.:|.|.|.|:..|..|.||:.:|.:|...|. ..|||...:.
 Worm   255 EEKVDDEEFTFRRARPHTDFRGTFQYASPNAHLQLELGRHDDIWSLMYMVAEFF-VELPWTSNEE 318

  Fly   280 DTLKERYQK------IGDTKRATPIEVLCDGHPEEFATYLRYVRRLDFFETPDYDFLRRLFQDLF 338
            ..|:|...:      ..|.|..:.:.....|..:|..   :.::..:::.:|.||.:.:.|:|..
 Worm   319 IALEELKNQSSILRLFSDDKNPSRLTPEMRGQLDEID---KNLKSCNYYSSPKYDIVYQFFKDSM 380

  Fly   339 DRKGYTDEGEFDWTGKTMSTPVGSLQTGHEVIISPNKDRHNVTAKTNAKGGVAAWPDVPKPGA 401
            .:...|....:||                |.|   .|...:.:.|:|.|.  |.|.:   |||
 Worm   381 TKAKVTWTTPYDW----------------ETI---GKSSEDFSKKSNGKR--AVWEN---PGA 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	87/404 (22%)
		S_TKc	62..335	CDD:214567	82/384 (21%)
		CK1gamma_C	354..428	CDD:289378	11/48 (23%)
C49C8.1	NP_501483.2	PKc_like	27..377	CDD:389743	82/384 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160820
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740