Protein Alignment gish and ttbk-8.2

DIOPT Version :10

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_500837.1
• Gene: ttbk-8.2 / 177341
• WormBaseID: WBGene00016541
• Length: 308
• Species: Caenorhabditis elegans
• Alignment Length: 300
• Identity: 79/300 - (26%)
• Similarity: 135/300 - (45%)
• Gaps: 33/300 - (11%)

  Fly    64 VGKKIGCGNFGEL-----RLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAPDGI 123
            :.||:|.|.||.:     ..||       .|:|:|....:...|.||......|....:.   ..
 Worm    19 IEKKLGEGGFGAVYRVFDATGK-------YAMKVEGANEQIQVLKLEVSVLNELSKRGNR---HF 73

  Fly   124 PRIYHLGTCGGRYNAMVLELLGLSLEDLFNI-CARKFSLKTVLMIAKQLLHRIEYVHSRHLIYRD 187
            .:|...|.. |.:|.:|:.|:|.||:||... .....|:...:.|..|.|..:|.:|:...::||
 Worm    74 CKIEDKGRF-GNFNYVVMTLVGKSLQDLNKAGVGGHMSMGCSIGIGIQSLEALEDLHNIGYLHRD 137

  Fly   188 VKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQS 252
            |||.|:.|||......:.::|:|||:.:::...|.....| |:.....||.:|..|:.|:.||..
 Worm   138 VKPGNYTIGRPELNEIRKVYILDFGMCRKFTGNDGTIRKP-RQAAGFRGTVKYAPISCHLQRELC 201

  Fly   253 RRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRA------TPIEVLCDGHPEEFAT 311
            |:||||...:|.:....|::|||.:      ....::|..|:|      |.....|   |::|..
 Worm   202 RKDDLETWMYMQVELSHGTIPWQHI------SDMNQVGQAKQAIRNNLGTLFPPPC---PQQFQD 257

  Fly   312 YLRYVRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDW 351
            .:|.|..:.:::.|:|..:..:.:..:...|..:...:||
 Worm   258 IMRMVDAMKYYDAPNYQAIYGMMRQAYGACGSNENAPYDW 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	78/299 (26%)
		CK1gamma_C	354..439	CDD:463640
ttbk-8.2	NP_500837.1	STKc_TTBK	16..281	CDD:270919	76/282 (27%)