DRSC/TRiP Functional Genomics Resources

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Protein Alignment gish and ttbk-2

DIOPT Version :9

Sequence 1:NP_001262624.1 Gene:gish / 49701 FlyBaseID:FBgn0250823 Length:537 Species:Drosophila melanogaster
Sequence 2:NP_500759.1 Gene:ttbk-2 / 177304 WormBaseID:WBGene00018122 Length:311 Species:Caenorhabditis elegans


Alignment Length:298 Identity:84/298 - (28%)
Similarity:134/298 - (44%) Gaps:29/298 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 VGKKIGCGNFGELRL-----GKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAPDGI 123
            :.||:|.|..|.:.|     ||       .|:|:|.:......|.:|   ..:||..........
 Worm    22 ITKKLGEGGCGAVYLCTDATGK-------YALKVEGISEAMQVLKME---VLVLGELTKRGSRHF 76

  Fly   124 PRIYHLGTCGGRYNAMVLELLGLSLEDLFNICARK-FSLKTVLMIAKQLLHRIEYVHSRHLIYRD 187
            .:|...|..|. :|.:|:.|:|.||:||....|:: .||...|.:..|.|..:|.:|:...::||
 Worm    77 CKIEDKGRYGS-FNYVVMTLVGKSLQDLRKGTAQQCLSLACSLSVGIQSLEALEDLHNIGYLHRD 140

  Fly   188 VKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQS 252
            |||.|:.|||......:.::|:|||:|:::.|.:.....| |......||.||..|..|..:|..
 Worm   141 VKPGNYTIGRAELNELRKVYILDFGMARKFTDNNGVIRKP-RAAAGFRGTVRYAPIACHKNQELG 204

  Fly   253 RRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRA---TPIEVLCDGHP-EEFATYL 313
            |:||:|...:|.:....|.:||:.:      .....:|..|:|   ||.::.....| .|....:
 Worm   205 RKDDVEVWLYMQVELTVGRVPWKEI------TDMNAVGQAKQAIRNTPEKMFVFPCPANELKEIM 263

  Fly   314 RYVRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDW 351
            :.|...|:|..|:|....||.:......| ..|..:||
 Worm   264 KMVDSWDYFADPNYADCYRLMKQTLANCG-KPEYPYDW 300

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
gishNP_001262624.1 STKc_CK1_gamma 61..354 CDD:271028 84/298 (28%)
S_TKc 62..335 CDD:214567 80/280 (29%)
CK1gamma_C 354..428 CDD:289378
ttbk-2NP_500759.1 STKc_TTBK 19..285 CDD:270919 80/280 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C160160832
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1164
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.740

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