Protein Alignment gish and kin-19

DIOPT Version :10

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001369852.1
• Gene: kin-19 / 175524
• WormBaseID: WBGene00002202
• Length: 341
• Species: Caenorhabditis elegans
• Alignment Length: 298
• Identity: 154/298 - (51%)
• Similarity: 207/298 - (69%)
• Gaps: 12/298 - (4%)

  Fly    57 MVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAPD 121
            :|...:::.:|||.|:||::.:..|:.|.|.||||:|..:::.|||..|.:.|::|....
 Worm    11 IVATKYKLIRKIGSGSFGDIYVSINVTNGEEVAIKLESNRARHPQLLYESKVYRILQGGV----- 70

  Fly   122 GIPRIYHLGTCGGRYNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIYR 186
            |||.|...|| ...||.:|::|||.|||||||.|:|:|::|||||:|.|::.||||||.::.|:|
 Worm    71 GIPHIRWYGT-EREYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMIGRIEYVHVKNFIHR 134

  Fly   187 DVKPENFL--IGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGR 249
            |:||:|||  |||...|    :.:|||||||:|.|..|..||||||.|:|||||||.|||.|:|.
 Worm   135 DIKPDNFLMGIGRHCNK----LFLIDFGLAKKYRDSRTRTHIPYREDKNLTGTARYASINAHLGI 195

  Fly   250 EQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLR 314
            |||||||:|:||::.|||.||:||||||||.|.|::|:||.:.|..|.:|.||.|.|.||..||.
 Worm   196 EQSRRDDMESLGYVLMYFNRGTLPWQGLKAATKKQKYEKISEKKMTTSVEHLCKGFPAEFPMYLS 260

  Fly   315 YVRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDWT 352
            |.|.|.|.|:|||.:||:||:.||....:..:..||||
 Worm   261 YTRGLRFDESPDYMYLRQLFRILFRTLNHQYDYTFDWT 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	153/294 (52%)
		CK1gamma_C	354..439	CDD:463640
kin-19	NP_001369852.1	STKc_CK1_alpha	15..280	CDD:271030	145/274 (53%)