Protein Alignment gish and C56C10.6

DIOPT Version :10

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_495333.1
• Gene: C56C10.6 / 174087
• WormBaseID: WBGene00016963
• Length: 422
• Species: Caenorhabditis elegans
• Alignment Length: 383
• Identity: 103/383 - (26%)
• Similarity: 169/383 - (44%)
• Gaps: 64/383 - (16%)

  Fly    27 NATTALAGGKSSSNNMYSTRQSVSTTTGVLMVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIK 91
            |.|..|..||                    :||.:::|.:|:|.|..|.:.|.|||.:....|:|
 Worm     9 NGTVELPKGK--------------------IVGCSWQVIRKLGEGGCGSVYLVKNLEDETEAAMK 53

  Fly    92 MEPMKSKAP-QLHLEYRFYKLLGSHADNAPDGIPRIYHLGTCGGRYNA-------MVLELLGLSL 148
            .|...:... .|.||....|.|        .|.|.:     |...:.|       :::.|||.||
 Worm    54 AESNGAAGGCVLKLEVAILKKL--------SGKPHV-----CQFLFAARLTDFTYVIMTLLGESL 105

  Fly   149 EDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIYRDVKPENFLIG-RTSTKREKIIHIIDFG 212
            ..:....||:.::.:.:.||..:|..::.:|....|:||:||.|..:| :|:....:..|::|||
 Worm   106 NKIVKRIARQITVSSQVRIAANVLFCLKQIHDIGFIHRDLKPANMALGYKTNNDECRFFHVLDFG 170

  Fly   213 LAKEYIDLDTNRHIPY-----REHKSLTGTARYMSINTHMGREQSRRDDLEALGHMFMYFLRGSL 272
            ||::::...:::....     ||.....||.||.||..|...||.|.|||.::.:: :..|||.|
 Worm   171 LARQFVVSQSDQPSKLMMRRPRERSLFRGTTRYCSIRMHDRAEQGRVDDLWSMVYL-LAELRGPL 234

  Fly   273 PWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRYVRRLDFFETPDYDFLRRLFQDL 337
            ||.. ::|.     :.:|:.||....||:....|.||....:|:|.|.:|..|||..:..|...:
 Worm   235 PWSS-QSDK-----RVVGEMKRLHSDEVVLQNSPMEFLEIAKYLRSLTYFHRPDYHKIFMLLISV 293

  Fly   338 FDRKGYTDEGEFDW-----TGKTMSTPVGSL-----QTGHEVIISPNKDRHNVTAKTN 385
            ..:..:.....|||     |..:.|||..|:     |...|.:...::::.....||:
 Worm   294 MSKGKFAWNDPFDWEMPISTTPSKSTPSKSVTKSPAQLSKETVKKASREKTLSKEKTS 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	88/311 (28%)
		CK1gamma_C	354..439	CDD:463640	8/37 (22%)
C56C10.6	NP_495333.1	Protein Kinases, catalytic domain	24..290	CDD:473864	83/285 (29%)
		CAF-1_p150	<326..>407	CDD:402959	4/26 (15%)