DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gish and C09D4.3

DIOPT Version :9

Sequence 1:	NP_001262624.1	Gene:	gish / 49701	FlyBaseID:	FBgn0250823	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_491610.1	Gene:	C09D4.3 / 172202	WormBaseID:	WBGene00015634	Length:	406	Species:	Caenorhabditis elegans

Alignment Length:	302	Identity:	91/302 - (30%)
Similarity:	142/302 - (47%)	Gaps:	28/302 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 GPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAPDGI 123
            |..|.:.:|:|.|..|.:.|  :::....||||.|  |.....|.:|.:....:..|     :|:
Worm    85 GDRFILRQKLGDGAMGHVFL--SIFGGRSVAIKAE--KYSTGMLPMEIKVLLSIRRH-----NGV 140

  Fly   124 P--RIYHLGTCGGRYNAMVLELLGLSLEDLFNICA----RKFSLKTVLMIAKQLLHRIEYVHSRH 182
            .  .|...||....||.|::.:||   :||:.:.|    |.|:|.|...||.:.:..||.:|:..
Worm   141 HFCDIIDYGTIRREYNYMIISILG---KDLYRLRAEQPTRSFTLNTTTKIALETIEAIEELHNIG 202

  Fly   183 LIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHM 247
            .:.|||||.||..|:....:.|.|.:.||||||::||.| |:.:..|......||.||.|:..|.
Worm   203 YLSRDVKPSNFAPGQRDNGQHKTIFMFDFGLAKKFIDRD-NKKLKSRGEVGWRGTVRYGSLQAHK 266

  Fly   248 GREQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTK---RATPIEVLCDGHPEEF 309
            ..:..||||:|...:|.:..|.|.|||:.:...||      :|.:|   |.....:..:..|.:|
Worm   267 RMDLGRRDDVECWFYMLIEMLVGELPWRHMSDRTL------VGQSKLSIRNESRRLFFNRTPRQF 325

  Fly   310 ATYLRYVRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDW 351
            .|.:..:....|...|:|..|:.|..::.......|..::||
Worm   326 ETIMDMIDGYSFEIRPEYRHLKALINEIRMENMIPDRCKWDW 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	90/300 (30%)
		S_TKc	62..335	CDD:214567	87/281 (31%)
		CK1gamma_C	354..428	CDD:289378
C09D4.3	NP_491610.1	PKc_like	87..343	CDD:389743	84/274 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810