DRSC/TRiP Functional Genomics Resources

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Protein Alignment gish and Y65B4A.9

DIOPT Version :10

Sequence 1:NP_001262624.1 Gene:gish / 49701 FlyBaseID:FBgn0250823 Length:537 Species:Drosophila melanogaster
Sequence 2:NP_001293249.1 Gene:Y65B4A.9 / 171658 WormBaseID:WBGene00022032 Length:391 Species:Caenorhabditis elegans


Alignment Length:440 Identity:113/440 - (25%)
Similarity:177/440 - (40%) Gaps:95/440 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    58 VGP-------------NFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFY 109
            |||             .:.|.|.:..|.||.:...|...:.:..|:|.|.:..|:..|.   :..
 Worm     4 VGPGQPQKELIRAQNGTYEVTKPLATGTFGSIYKVKRESDGKFFAVKCEALNMKSSLLR---QMS 65

  Fly   110 KLLGSHADNAPDGIPRIYHLGTCGGRYNAMVLELLGLSLEDLFNICA-----RKFSLKTVLMIAK 169
            .:|.|....:| ....|...||...|:..:|:.|.|   |:|:.:..     ||||:.|.|.:|:
 Worm    66 VVLASIHHPSP-FFTNIEERGTVPNRFLFIVMPLYG---ENLYELMMNTNKDRKFSMATGLHLAE 126

  Fly   170 QLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKS- 233
            |.|..|..:|....|:||:||.:|.|||....:...::::||||.|....:..|.....:..|: 
 Worm   127 QTLAAIRDLHRNGFIHRDIKPSHFCIGREIDGQHHQVYLLDFGLCKRPRFVKKNDEAEEQMRKNA 191

  Fly   234 --LTGTARYMSINTHMGREQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKR-- 294
              ..|..:|.|::.|.|:....:||:|:..:|.:.|..|:|||..|.    ||..|.:...||  
 Worm   192 IHYRGVVKYASVHAHQGKNLGYKDDMESWWYMVLEFFLGALPWALLN----KESEQDVLHLKRRI 252

  Fly   295 -ATPIEVLCDGHPEEFATY---LRYVRR-LDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDWTGK 354
             |..:..:....||..|.:   |..:|. .|..|..:||.:....|.||::.....:...||...
 Worm   253 TAPMVASVWRTTPETTAGFFDLLTIIREPKDVAEFVEYDRIADGIQKLFEKSKSNTQEPPDWDCM 317

  Fly   355 TMSTPVGSLQTGHEVIISPNKDRHNVTAKTNAKGGVAAWPDVP-KPGATLGNLTPADRHGSVQVV 418
            |.....|..|.   ::|:|                    |:|. ||....|.             
 Worm   318 TDYKGPGYQQV---LMIAP--------------------PEVGLKPEMDFGK------------- 346

  Fly   419 SSTNGELNPDDPTAGHSNTPITQQPEVEVVDETKCCCFFKRKKKKSTRQK 468
                     .||.||..:   .:||:.|.||:       |:||||.:::|
 Worm   347 ---------SDPGAGGES---GEQPKKEDVDK-------KKKKKKKSKKK 377

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
gishNP_001262624.1 STKc_CK1_gamma 61..354 CDD:271028 85/307 (28%)
CK1gamma_C 354..439 CDD:463640 14/85 (16%)
Y65B4A.9NP_001293249.1 STKc_TTBK 20..302 CDD:270919 82/292 (28%)

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