Protein Alignment gish and TTBK2

DIOPT Version :9

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: XP_005254228.1
• Gene: TTBK2 / 146057
• HGNCID: 19141
• Length: 1250
• Species: Homo sapiens
• Alignment Length: 432
• Identity: 131/432 - (30%)
• Similarity: 195/432 - (45%)
• Gaps: 82/432 - (18%)

  Fly   132 CG--GRYNAMVLELLGLSLEDLFNICAR-KFSLKTVLMIAKQLLHRIEYVHSRHLIYRDVKPENF 193
            ||  .|:|.:|::|.|.:|.||....:| .|::.|.|.:.:|:|..||.:||...::||:||.||
Human    89 CGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNF 153

  Fly   194 LIGR-TSTKREKIIHIIDFGLAKEYIDL--DTNRHIPYREHKSLTGTARYMSINTHMGREQSRRD 255
            .:|| .||.|:  .:::|||||:::.:.  |..   |.|......||.||.|||.|..||..|.|
Human   154 AMGRFPSTCRK--CYMLDFGLARQFTNSCGDVR---PPRAVAGFRGTVRYASINAHRNREMGRHD 213

  Fly   256 DLEALGHMFMYFLRGSLPWQGLK----ADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRYV 316
            ||.:|.:|.:.|:.|.|||:.:|    ..::||||..          .::....|.||:.:|.::
Human   214 DLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDH----------RLMLKHLPPEFSIFLDHI 268

  Fly   317 RRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDW--TGKTMSTPVGSLQTGHEVIISPNKDRHN 379
            ..||:|..|||..|..:|.:.....|..:...|||  ||..     |||.|   ...|.....|
Human   269 SSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWEKTGND-----GSLTT---TTTSTTPQLH- 324

  Fly   380 VTAKTNAKGGVAAWPDVPKPGATLGNLT----PADRHGSVQVVSSTNG---ELNPD--DPTAGHS 435
             |..|.|..|:|  ...|.||..|...|    |.:     |:....||   .::||  ..:.||
Human   325 -TRLTPAAIGIA--NATPIPGDLLRENTDEVFPDE-----QLSDGENGIPVGVSPDKLPGSLGH- 380

  Fly   436 NTPITQQPEV-EVVDETK------CCCFFKRKKKKSTRQKXLDGVQCSPEREAVTLLRATSHSN- 492
              |..|:.:| |.:|..|      .|       |.:|.::...|       :|..||.|.|..:
Human   381 --PRPQEKDVWEEMDANKNKIKLGIC-------KAATEEENSHG-------QANGLLNAPSLGSP 429

  Fly   493 -SRDSVLNNPSQD--YIQQATSQHTLRYPPSASMLTPTPTTN 531
             ...|.:..|.:|  .:::..|.|:.......: |.|.|.|:
Human   430 IRVRSEITQPDRDIPLVRKLRSIHSFELEKRLT-LEPKPDTD 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	82/233 (35%)
		S_TKc	62..335	CDD:214567	76/212 (36%)
		CK1gamma_C	354..428	CDD:289378	20/80 (25%)
TTBK2	XP_005254228.1	PKc_like	75..287	CDD:304357	76/212 (36%)
		SPS1	78..>267	CDD:223589	69/192 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810