Protein Alignment gish and CSNK1G2

DIOPT Version :10

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: XP_005259555.1
• Gene: CSNK1G2 / 1455
• HGNCID: 2455
• Length: 445
• Species: Homo sapiens
• Alignment Length: 460
• Identity: 291/460 - (63%)
• Similarity: 338/460 - (73%)
• Gaps: 62/460 - (13%)

  Fly    33 AGGKSSSNNMYSTRQSVSTTTGVLMVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKS 97
            |||..||:.:    :|..|::||||||||||||||||||||||||||||||.||:||||:||:||
Human    21 AGGGRSSHGI----RSSGTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKS 81

  Fly    98 KAPQLHLEYRFYKLLGS-------------------------HADNAPDGIPRIYHLGTCGGRYN 137
            :||||||||||||.|.:                         ...:|.:|:|::|:.|.| |:||
Human    82 RAPQLHLEYRFYKQLSATGTGRPAGGAGAAQGQGGGCRRTPVRLSSAAEGVPQVYYFGPC-GKYN 145

  Fly   138 AMVLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIYRDVKPENFLIGRTSTKR 202
            ||||||||.||||||::|.|.|:||||||||.||:.|:||||::.||||||||||||:||..|||
Human   146 AMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKR 210

  Fly   203 EKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQSRRDDLEALGHMFMYF 267
            :..||||||||||||||.:|.:||||||||||||||||||||||:|:||||||||||||||||||
Human   211 QHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYF 275

  Fly   268 LRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRYVRRLDFFETPDYDFLRR 332
            |||||||||||||||||||||||||||||||||||:..|||.||||||||||||||.||||:||:
Human   276 LRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRK 340

  Fly   333 LFQDLFDRKGYTDEGEFDWTGKTMSTPVGSLQTGHEVIISPNKDRHNVTAKTNAKGGVAAWPDVP 397
            ||.|||||.|:..:.|:||.||.:.||:|::.|                             |:|
Human   341 LFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHT-----------------------------DLP 376

  Fly   398 KPGATLGNLTPADRHGSVQVVSSTNGELNPDDPTAGHSNTPITQQPEVEVVDETKCCCFFKRKKK 462
            ..........|   |...|.::|||||||.|||||||||.|||...||||.|||||||||||:|:
Human   377 SQPQLRDKTQP---HSKNQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKCCCFFKRRKR 438

  Fly   463 KSTRQ 467
            ||.::
Human   439 KSLQR 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	229/317 (72%)
		CK1gamma_C	354..439	CDD:463640	26/84 (31%)
CSNK1G2	XP_005259555.1	STKc_CK1_gamma	45..362	CDD:271028	229/317 (72%)
		CK1gamma_C	362..415	CDD:463640	26/84 (31%)