Protein Alignment gish and CSNK1A1

DIOPT Version :9

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001020276.1
• Gene: CSNK1A1 / 1452
• HGNCID: 2451
• Length: 365
• Species: Homo sapiens
• Alignment Length: 383
• Identity: 171/383 - (44%)
• Similarity: 230/383 - (60%)
• Gaps: 63/383 - (16%)

  Fly    48 SVSTTTGVLMVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLL 112
            |.|.:....:||..:::.:|||.|:||::.|..|:.|.|.||:|:|..|::.|||..|.:.||:|
Human     3 SSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKIL 67

  Fly   113 GSHADNAPDGIPRIYHLGTCGGRYNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEY 177
            ....     |||.|...|. ...||.:|::|||.|||||||.|:|:|::|||||:|.|::.||||
Human    68 QGGV-----GIPHIRWYGQ-EKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEY 126

  Fly   178 VHSRHLIYRDVKPENFLIG--------------------RTSTKRE------KIIHIIDFGLAKE 216
            ||:::.|:||:||:|||:|                    ..||.::      ..:.:|||||||:
Human   127 VHTKNFIHRDIKPDNFLMGIGRHCNKCLESPVGKRKRSMTVSTSQDPSFSGLNQLFLIDFGLAKK 191

  Fly   217 YIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQSRRDDLEALGHMFMYFLRGSLPWQGLKADT 281
            |.|..|.:||||||.|:|||||||.|||.|:|.|||||||:|:||::.|||.|.|||||||||.|
Human   192 YRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAAT 256

  Fly   282 LKERYQKIGDTKRATPIEVLCDGHPEEFATYLRYVRRLDFFETPDYDFLRRLFQDLFDRKGYTDE 346
            .|::|:||.:.|.:||:||||.|.|.|||.||.|.|.|.|.|.|||.:||:||:.||....:..:
Human   257 KKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYD 321

  Fly   347 GEFDWT----------------GKTMSTPVGSLQTGHEVIISPNKDRHNVTAKTNAKG 388
            ..||||                |:...||.|. ||          |:    .|:|.||
Human   322 YTFDWTMLKQKAAQQAASSSGQGQQAQTPTGK-QT----------DK----TKSNMKG 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	156/334 (47%)
		S_TKc	62..335	CDD:214567	149/298 (50%)
		CK1gamma_C	354..428	CDD:289378	10/35 (29%)
CSNK1A1	NP_001020276.1	STKc_CK1_alpha	16..309	CDD:271030	148/298 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910