Protein Alignment gish and CSNK1A1L

DIOPT Version :9

• Sequence 1: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_660204.2
• Gene: CSNK1A1L / 122011
• HGNCID: 20289
• Length: 337
• Species: Homo sapiens
• Alignment Length: 341
• Identity: 162/341 - (47%)
• Similarity: 220/341 - (64%)
• Gaps: 33/341 - (9%)

  Fly    56 LMVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAP 120
            |:||..:::.:|||.|:||::.||....|.|.||:|:|..|.|.|||..|.:.|.:|....
Human    11 LVVGGKYKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLYESKLYTILQGGV---- 71

  Fly   121 DGIPRIYHLGTCGGRYNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIY 185
             |||.::..|..... |.:|::|||.|||||||.|:|:|::|||||:|.|::.||||||:::.::
Human    72 -GIPHMHWYGQEKDN-NVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFLH 134

  Fly   186 RDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGRE 250
            ||:||:|||:| |.....|:. :|||||||:|.|..|.:||||||.|.|.||.||.|||.|:|.|
Human   135 RDIKPDNFLMG-TGRHCNKLF-LIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIE 197

  Fly   251 QSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRY 315
            ||||||:|:||::||||.|.|||||||:|.|.|::|:||.:.|.:||:||||.|.|.|||.||.|
Human   198 QSRRDDMESLGYVFMYFNRTSLPWQGLRAMTKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNY 262

  Fly   316 VRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDWT----------------GKTMSTPVGSLQ 364
            .|.|.|.|.|||.:||:||:.||....:..:..||||                |:...|     |
Human   263 CRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQT-----Q 322

  Fly   365 TGHEVIISPNKDRHNV 380
            ||.:.    .|:::||
Human   323 TGKQT----EKNKNNV 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	151/308 (49%)
		S_TKc	62..335	CDD:214567	144/272 (53%)
		CK1gamma_C	354..428	CDD:289378	7/27 (26%)
CSNK1A1L	NP_660204.2	STKc_CK1_alpha	16..281	CDD:271030	143/272 (53%)
		SPS1	16..>239	CDD:223589	119/230 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	309..337		8/35 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810