Protein Alignment src and Src42A

DIOPT Version :9

• Sequence 1: XP_017953215.1
• Gene: src / 496893
• XenbaseID: XB-GENE-489820
• Length: 544
• Species: Xenopus tropicalis
• Sequence 2: NP_610191.2
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1597
• Species: Drosophila melanogaster
• Alignment Length: 565
• Identity: 262/565 - (46%)
• Similarity: 332/565 - (58%)
• Gaps: 87/565 - (15%)

 Frog    10 KPREGGPRSRSLDIAEGSHQPFTSLSASQTP---SKSLD---------SHRQPAQPFGGNCDL-- 60
            :||....:.|.|.    .||        |||   ..|||         :.|||.:.:.....|
  Fly  1080 RPRRSLKQHRCLQ----QHQ--------QTPLAKKHSLDNCLQVVSSTTSRQPLRRWSNQTPLKC 1132

 Frog    61 --------TPFGGVNFSDTITSPQRIGPLAGGVTTFVALYDYESRT-----ETDL-SFKKGERLQ 111
                    .|...:..|.::  |.............:::.|....|     :|.| :.|||:..:
  Fly  1133 TCHPATEELPLTAIEKSRSL--PAACSASCSHTCAHLSVIDQSPATTKCFGKTSLTTAKKGKSRR 1195

 Frog   112 IVNNTRPDMREGDWWLARSLSSGQTGYIPSNYVAPSDSIQAEEWYLGKITRREAERLLLSLENPR 176
            :...||                             .:.:..:.||..||.|.|||:.||..||..
  Fly  1196 LSEFTR-----------------------------GEFLNEKSWYFRKIKRIEAEKKLLLPENEH 1231

 Frog   177 GTFLVRESETTKGAYCLSVSDYDANRGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHA 241
            |.||:|:||:....|.|||.|.|     .||||:||:||.|||:|..||.|.:||:||.:|||.:
  Fly  1232 GAFLIRDSESRHNDYSLSVRDGD-----TVKHYRIRQLDEGGFFIARRTTFRTLQELVEHYSKDS 1291

 Frog   242 DGLCHRLTTVC-PTAKPQTQGLS---KDAWEIPRDSLRLELKLGQGCFGEVWMGVSVGTWNGTTR 302
            ||||..|...| ...||.|:|||   :|.|||.|.||:...|||.|.||:||.|:    ||.||.
  Fly  1292 DGLCVNLCKPCVQIEKPVTEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEGL----WNNTTP 1352

 Frog   303 VAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVS-EEPIYIVTEYMSKGSLLDFLK--GE 364
            |||||||.|||.|:.||.|||:||||||.||:|||||.: ||||||:||.|..||||::|:  ..
  Fly  1353 VAIKTLKSGTMDPKDFLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAG 1417

 Frog   365 MGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTA 429
            .||.|::..|:|||||||:||||:|..||:||||.|.|:|||:..:.|:|||||||||:::||.|
  Fly  1418 KGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDEYEA 1482

 Frog   430 RQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPC 494
            |.||:|||||||||||.|.:|:|||||||||||||||.|.||:|||||.|.|||.|||.|||||.
  Fly  1483 RVGARFPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQ 1547

 Frog   495 PPDCPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTATEPQYQ 539
            ||:|...|:::|.:||.|||..|||||.||..|||::|:.:..|:
  Fly  1548 PPNCEPRLYEIMLECWHKDPMRRPTFETLQWKLEDFYTSDQSDYK 1592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
src	XP_017953215.1	None
Src42A	NP_610191.2	SH2_Src_Src42	1210..1301	CDD:198233	51/95 (54%)
		PTKc_Frk_like	1319..1587	CDD:270653	175/271 (65%)
		Pkinase_Tyr	1328..1580	CDD:285015	165/255 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I8785
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248674at33208
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010