Protein Alignment OGG1 and Ogg1

DIOPT Version :9

• Sequence 1: NP_058214.1
• Gene: OGG1 / 4968
• HGNCID: 8125
• Length: 424
• Species: Homo sapiens
• Sequence 2: NP_572499.2
• Gene: Ogg1 / 31806
• FlyBaseID: FBgn0027864
• Length: 343
• Species: Drosophila melanogaster
• Alignment Length: 291
• Identity: 105/291 - (36%)
• Similarity: 159/291 - (54%)
• Gaps: 14/291 - (4%)

Human    32 ELRLDLVLPSGQSFRWR---EQSPAHWSGVLADQVWTLTQTEEQLHCTVYRGDKSQASRPTPDEL 93
            |..|:..|..|||||||   :.:...:.||:.:..|.|.|.|..:....| |..|..:  |.|..
  Fly    33 ECDLERTLLGGQSFRWRSICDGNRTKYGGVVFNTYWVLQQEESFITYEAY-GTSSPLA--TKDYS 94

Human    94 EAVRKYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGM 158
            ..:..|.::|..|......|.|.|.:|.:...|  .||||.|:|.|.:|||:||.||||.||:.|
  Fly    95 SLISDYLRVDFDLKVNQKDWLSKDDNFVKFLSK--PVRLLSQEPFENIFSFLCSQNNNIKRISSM 157

Human   159 VERLCQAFGPRLIQLDDVTYHGFPSLQA---LAGPEVEAHLRKLGLGYRARYVSASARAILEEQG 220
            :|..|..||.::...:....:.||::..   :...::.|.||....||||::::.:.:.| :::|
  Fly   158 IEWFCATFGTKIGHFNGADAYTFPTINRFHDIPCEDLNAQLRAAKFGYRAKFIAQTLQEI-QKKG 221

Human   221 GLAWLQQLRESSYEEAHKALCILPGVGTKVADCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTT 285
            |..|...|:...:|:|.:.|.:|||:|.|||||||||::...::||||:|::.|||..|..|.|.
  Fly   222 GQNWFISLKSMPFEKAREELTLLPGIGYKVADCICLMSMGHLESVPVDIHIYRIAQNYYLPHLTG 286

Human   286 SQAKGPSPQTNKELGNFFRSLWGPYAGWAQA 316
            .  |..:.:..:|:...|:.|.|.|||||||
  Fly   287 Q--KNVTKKIYEEVSKHFQKLHGKYAGWAQA 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OGG1	NP_058214.1	ogg	11..322	CDD:211589	105/291 (36%)
		OGG_N	25..141	CDD:285211	36/111 (32%)
		ENDO3c	139..319	CDD:238013	70/181 (39%)
Ogg1	NP_572499.2	OGG_N	26..140	CDD:285211	36/111 (32%)
		ogg	33..324	CDD:211589	105/291 (36%)
		ENDO3c	137..318	CDD:238013	70/182 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160042
Domainoid	1	1.000	115	1.000	Domainoid score	I6041
eggNOG	1	0.900	-	-		E1_COG0122
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1909
Inparanoid	1	1.050	195	1.000	Inparanoid score	I3830
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55194
OrthoDB	1	1.010	-	-		D1079482at2759
OrthoFinder	1	1.000	-	-		FOG0005614
OrthoInspector	1	1.000	-	-		oto89259
orthoMCL	1	0.900	-	-		OOG6_102483
Panther	1	1.100	-	-	LDO	PTHR10242
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2212
SonicParanoid	1	1.000	-	-		X4591
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800