Protein Alignment hrg and Papolg

DIOPT Version :10

• Sequence 1: NP_001261097.1
• Gene: hrg / 49636
• FlyBaseID: FBgn0015949
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_001100714.1
• Gene: Papolg / 305586
• RGDID: 1310337
• Length: 739
• Species: Rattus norvegicus
• Alignment Length: 756
• Identity: 361/756 - (47%)
• Similarity: 466/756 - (61%)
• Gaps: 78/756 - (10%)

  Fly    26 KQLGMTSAISLAEPRPEDLQRTDELRGSLEPYNVFESQDELNHRMEILAKLNTLVKQWVKEISVS 90
            |..|:||.||||.|:..|...|.:|..:::|:.|||.::|||||:.:|.|||.|||:|:.:||.|
  Rat    17 KHYGITSPISLACPKEIDHIYTQKLIDAMKPFGVFEDEEELNHRLVVLGKLNNLVKEWISDISES 81

  Fly    91 KNMPESAAEKLGGKIYTFGSYRLGVHHKGADIDALCVAPRNIERTDYFQSFFEVLKKQPEVTECR 155
            ||:|.|....:||||:||||||||||.|||||||||||||::||:|:||||||.||.|..|...|
  Rat    82 KNLPPSVVATVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVERSDFFQSFFEKLKHQDGVRNLR 146

  Fly   156 SVEEAFVPVIKMNFDGIEIDLLFARLSLKEIPDDFDLRDDNLLRNLDHRSVRSLNGCRVTDEILA 220
            :||:|||||||..||||||||:||||:::.|.|:.|||||:.||:||.|.:|||||||||||||.
  Rat   147 AVEDAFVPVIKFEFDGIEIDLVFARLAIQTISDNLDLRDDSRLRSLDIRCIRSLNGCRVTDEILH 211

  Fly   221 LVPNIENFRLALRTIKLWAKKHGIYSNSLGYFGGVTWAMLVARTCQLYPNAAAATLVHKFFLVFS 285
            ||||.|.|||.||.:|||||:.|||||.||:.|||:|||||||||||||||||:|||||||||||
  Rat   212 LVPNKETFRLTLRAVKLWAKRRGIYSNMLGFLGGVSWAMLVARTCQLYPNAAASTLVHKFFLVFS 276

  Fly   286 RWKWPNPVLLKHPDNVNLRFQVWDPRVNASDRYHLMPIITPAYPQQNSTFNVSESTKKVILTEFN 350
            :|:||||||||.|:..||...|||||||.||||||||||||||||||||:|||.||:.|::.||.
  Rat   277 KWEWPNPVLLKQPEESNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSTSTRTVMVEEFK 341

  Fly   351 RGMNITDEIMLGRIPWERLFEAPSFFYRYRHFIVLLVNSQTADDHLEWCGLVESKVRLLIGNLER 415
            :|:.:||||:.|:..|.:|.|.|:||.:|||:|||..::.|.::||||.||||||:|:|:|||||
  Rat   342 QGLAVTDEILQGKSDWSKLLEPPNFFQKYRHYIVLTASASTEENHLEWVGLVESKIRVLVGNLER 406

  Fly   416 NPHIALAHVNPKCFEFKKGQSANNSQNNSGNEDDLKQSQGNQSAVTSAPFCSMWFIGLEFERSEN 480
            |..|.||||||:.|   .|...::..||                     :.||||:|:.|.|.||
  Rat   407 NEFITLAHVNPQSF---PGNKEHHKANN---------------------YVSMWFLGIIFRRVEN 447

  Fly   481 ---LNVDLTESIQNFTEHVMMHGVNIKMLKEGMTIDARHVKRKQLSLYLDSDFLKRERKSMESHN 542
               :|:|||..||:||:.|.....||.|||:||.|:|.|||:|||..||.::.|::::||:...:
  Rat   448 AESVNIDLTYDIQSFTDTVYRQANNINMLKDGMKIEATHVKKKQLHHYLPAEILQKKKKSLSDVS 512

  Fly   543 NFNNTLLANRKRLSTELAQSQ---DPLPPGQQPSSGNRGRDSGAKIQRLSDSLT--EENSNAS-- 600
            ..:..|.:.|..|.:....|.   |...|...|.|.::..:        .||.|  .|.|||.
  Rat   513 RSSGGLQSKRSSLDSNCLDSSRDTDSGTPFNSPGSAHKPSN--------PDSPTGDAERSNAEPM 569

  Fly   601 SDMGAGTPTTPTTAQLSAPSFKSSGKNGSEIDVVEQEPTQPHNNGNASSNTTTTEVACSXQPPTL 665
            :.:....|:.|....||.|...:.|      |...:..:.|      :..|..|.|..| .|...
  Rat   570 AVIVEKLPSVPPAQGLSIPVIGAKG------DAAVKAVSSP------AVCTIPTVVGRSVIPRVT 622

  Fly   666 HPHPPHQ-QP-------------PPAPPQPPA-----HHHHHQKFRKNNNA--AAAAASNSIFNQ 709
            .||.|.| ||             |.....||.     .....:||.:..:|  .:.||.:   .:
  Rat   623 TPHNPVQGQPHLNGISNITKNVTPKRSHSPPTDGTAKRLKDIEKFIRLESAFKESRAAED---RK 684

  Fly   710 RSILHAASSLSAALSITGHKRKQQTATSTTMISSSNIAHSN 750
            |..:.|....|..:......||::..:.....|||.:..||
  Rat   685 RKPMDAIGGESMPIPTIDTSRKKRLPSKELPDSSSPVPASN 725

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrg	NP_001261097.1	PAP_central	29..371	CDD:461486	230/341 (67%)
		PAP_RNA-bind	374..534	CDD:461484	74/162 (46%)
Papolg	NP_001100714.1	PAP_central	20..363	CDD:461486	230/342 (67%)
		PAP_RNA-bind	366..503	CDD:461484	74/160 (46%)
		PTZ00449	<489..719	CDD:185628	56/252 (22%)