Protein Alignment hrg and Papolb

DIOPT Version :10

• Sequence 1: NP_001261097.1
• Gene: hrg / 49636
• FlyBaseID: FBgn0015949
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_001012020.1
• Gene: Papolb / 304300
• RGDID: 1310946
• Length: 642
• Species: Rattus norvegicus
• Alignment Length: 700
• Identity: 338/700 - (48%)
• Similarity: 435/700 - (62%)
• Gaps: 94/700 - (13%)

  Fly    18 STSG----GPPAKQLGMTSAISLAEPRPEDLQRTDELRGSLEPYNVFESQDELNHRMEILAKLNT 78
            :|.|    .|..||.|::|.||||.|:..|.:.|.:|..:|:|:.|||.::||..|:.||.|||.
  Rat     7 TTQGAQQPAPAPKQYGISSPISLAAPKDTDRELTQKLIETLQPFGVFEEEEELQRRILILQKLNN 71

  Fly    79 LVKQWVKEISVSKNMPESAAEKLGGKIYTFGSYRLGVHHKGADIDALCVAPRNIERTDYFQSFFE 143
            |||:|::|||.|:|:|::..|.:||||:||||||||||.|||||||||||||:::|.|:|.||::
  Rat    72 LVKEWIREISESRNLPQAVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVDRNDFFTSFYD 136

  Fly   144 VLKKQPEVTECRSVEEAFVPVIKMNFDGIEIDLLFARLSLKEIPDDFDLRDDNLLRNLDHRSVRS 208
            .||.|.||.:.|:||||||||||:.|||||||:|||||:|:.||:|.|||||:||:|||.|.:||
  Rat   137 KLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRS 201

  Fly   209 LNGCRVTDEILALVPNIENFRLALRTIKLWAKKHGIYSNSLGYFGGVTWAMLVARTCQLYPNAAA 273
            |||||||||||.|||||::|||.||.||||||.|.||||.||:.|||:|||||||||||||||.|
  Rat   202 LNGCRVTDEILHLVPNIDSFRLTLRAIKLWAKCHNIYSNILGFLGGVSWAMLVARTCQLYPNAIA 266

  Fly   274 ATLVHKFFLVFSRWKWPNPVLLKHPDNVNLRFQVWDPRVNASDRYHLMPIITPAYPQQNSTFNVS 338
            :|||.|||||||.|:||||||||.|:..||...|||||||.||||||||||||||||||||:|||
  Rat   267 STLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVS 331

  Fly   339 ESTKKVILTEFNRGMNITDEIMLGRIPWERLFEAPSFFYRYRHFIVLLVNSQTADDHLEWCGLVE 403
            .||:.|::.||.:|:.||.||:|.:..|.:||||||||.:|:|:||||.::.|...||||.||||
  Rat   332 VSTRMVMIEEFKQGLAITHEILLNKAEWSKLFEAPSFFQKYKHYIVLLASAPTEKQHLEWVGLVE 396

  Fly   404 SKVRLLIGNLERNPHIALAHVNPKCFEFKKGQSANNSQNNSGNEDDLKQSQGNQSAVTSAPFCSM 468
            ||:|:|:|:||:|..|.||||||:.|...|        .|...|:                |.:|
  Rat   397 SKIRILVGSLEKNEFITLAHVNPQSFPAPK--------ENVDKEE----------------FRTM 437

  Fly   469 WFIGLEFERSEN---LNVDLTESIQNFTEHVMMHGVNIKMLKEGMTIDARHVKRKQLSLYLDSDF 530
            |.|||..::.||   |::|||..||:||:.|....:|.||.:..|.|.|.|::||:|...|.:..
  Rat   438 WVIGLVLKKPENSEILSIDLTYDIQSFTDTVYRQAINSKMFEMDMKIAAMHLRRKELHQLLPNHV 502

  Fly   531 LKRERKSMESHNNFNNTLLANRKRLSTELAQSQDPLPPGQQPSSGNRGRDSGAKIQRLSDSLTEE 595
            |:::    |:|              .||                       |.::..::||....
  Rat   503 LQKK----ETH--------------LTE-----------------------GVRLTAVNDSSLLL 526

  Fly   596 NSNASSDMGAGTPT-TPTTAQLSAPSFKSSGKNGSEIDVVEQEPTQ--------PHNNGNASSNT 651
            :.::.:.|.|.:|| |..|..|:|   ...|:|...:.|:....|.        .|.|...||..
  Rat   527 SIDSENSMTAPSPTGTIKTGPLTA---NPQGRNSPALAVMAASVTNIQFPDVSLQHVNPIESSGI 588

  Fly   652 TTTEVACSXQPPTLHPHPPHQQPPPAPPQ----PPAHHHHHQKFRKNNNA 697
            ..:|....       |..|...|||.|..    ...|..:|......|.|
  Rat   589 ALSESIAQI------PSQPTISPPPKPTMTRVVSSTHLVNHPSRPSGNTA 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hrg	NP_001261097.1	PAP_central	29..371	CDD:461486	229/341 (67%)
		PAP_RNA-bind	374..534	CDD:461484	66/162 (41%)
Papolb	NP_001012020.1	PAP_central	22..364	CDD:461486	229/341 (67%)
		PAP_RNA-bind	367..496	CDD:461484	64/152 (42%)