Protein Alignment Invadolysin and Gm29776

DIOPT Version :9

• Sequence 1: NP_652072.1
• Gene: Invadolysin / 49580
• FlyBaseID: FBgn0086359
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: NP_001357821.1
• Gene: Gm29776 / 101056084
• MGIID: 5588935
• Length: 698
• Species: Mus musculus
• Alignment Length: 684
• Identity: 162/684 - (23%)
• Similarity: 245/684 - (35%)
• Gaps: 214/684 - (31%)

  Fly    64 PARHSVRRRSVAAEQPLRILLVYDESVYRLEEEKFNLINDT----VLPEAVQFWEQALMVRETKG 124
            |..|..|        ||||...|..:  .:..|.::...:|    .:.|..:..:..|.|...:|
Mouse    47 PGSHEPR--------PLRIQTYYSRA--PVPGEAWDPEGETRALAAVTETTRRIQGILAVLPVQG 101

  Fly   125 VIRLNRKCDSTQVYVKNGHTHCI---------DHCKATT------MCGEVQVPDAHLDVCRVCNA 174
            .:.|:|  |..|      :.|.:         ..|....      .|...::|||||....:...
Mouse   102 PLLLSR--DPAQ------YCHAVWGDPDTPNYQRCSILNPGYKGESCLGAKIPDAHLRGYSLWPE 158

  Fly   175 TGQNCRIDSNTQP-GEGIENADFVFYVSARQTQRCFKGLTV-AYAAHCQQEAALDRPIAGHANLC 237
            .|    :....|| |.|::||||:.||....|.:|.|..:| ||||.||.::. |||:||....|
Mouse   159 HG----LPQLIQPDGPGVQNADFLLYVQVAHTSKCHKEPSVIAYAACCQLDSE-DRPLAGTIVYC 218

  Fly   238 PESISTKPQELQTLISTVKHEILHALGFSVSLYAFFRDDDGKPRTPRKLDTGKPYLNEKLQIHQW 302
            .:.:.:.......::....||:|||||||..|:..:||      .|..|.
Mouse   219 GQHLRSPTLSHDDIVMATLHELLHALGFSGQLFKMWRD------CPSGLS--------------- 262

  Fly   303 SNETIRKVVRENWSVRGGHVNKVVD--------MMVTPRVIAEVRAHFNC-NKLEGAELEDQGGE 358
                    .|||.|.|     |.|.        ::.||.|...:..|... ..|:||.||:   :
Mouse   263 --------ARENCSTR-----KQVTRRDERGQLLLTTPAVSHSLAKHLGVPGTLQGAPLEE---K 311

  Fly   359 GTALTHWEKRILENEAMTGT-----HTQSPVFSRITLALMEDSGWYRANYSMATPLTWGKGLGCA 418
            |:..:|||.|:|:...||.|     ||:   ...:|||..||||||:.|:|.|..|.||:|.|..
Mouse   312 GSLSSHWESRLLQGSIMTATFHGAQHTR---LDPVTLAAFEDSGWYQVNHSAAEELLWGQGSGPD 373

  Fly   419 FAMRSCKDWIQYNHARGRSIHPFCSKVKQDPLQTECTDDRNSVALCNLIRHEFELPKGYQNFDSL 483
            |.:.|.        .|..|...||:               .|...|    |...|.||..:.|
Mouse   374 FGLVST--------CRTGSSDFFCT---------------GSGLGC----HYLHLDKGSCDSD-- 409

  Fly   484 NHVKDGEEGFYGGSVSLADHCPYIQEFTWRSKNVIVRGSHCRFTEN--NPRPEKNFALESYGEGA 546
                           |..:.|        |....:.:||.|...||  :.|.|.... |.|...:
Mouse   410 ---------------STLEGC--------RIYKPLAKGSECWKEENGLHTRAENPHG-EIYHRHS 450

  Fly   547 KCF---DHSESMWEERSCHQTREWQHWGSGCYKYDCFDGRLHILVGNYSYKCSFPGQKLSIRIAA 608
            :||   ..|:.:.:..|...|.......:||    |           |.::|:..| ...:::..
Mouse   451 RCFLANLTSQVLSKHTSQPSTAPDLEDPTGC----C-----------YLHQCTHKG-AYEVQVEG 499

  Fly   609 NGWL------------HKGAIMCPPCHELCGAQFAAQGKQCRPGE-----EPDPLNKYPRDNL-- 654
            :.|:            :.|.:.||            ||:.|...|     ...|::...:|.|
Mouse   500 SPWIPCLPGKAVQIPGYDGLLYCP------------QGRLCLRDEGARAATSQPMSFTTQDLLSQ 552

  Fly   655 -----------ACGAGSEKSRSVAIITAVLLLFG 677
                       :.|.|..:..:..::.|:::..|
Mouse   553 LSLRLTGTPGHSLGKGQREELAEVVLQALVMRAG 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Invadolysin	NP_652072.1	Peptidase_M8	93..628	CDD:302875	143/586 (24%)
Gm29776	NP_001357821.1	Peptidase_M8	<133..524	CDD:388572	131/516 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10942
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010