Protein Alignment Invadolysin and lmln

DIOPT Version :9

• Sequence 1: NP_652072.1
• Gene: Invadolysin / 49580
• FlyBaseID: FBgn0086359
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: XP_031749166.1
• Gene: lmln / 100487583
• XenbaseID: XB-GENE-1010117
• Length: 667
• Species: Xenopus tropicalis
• Alignment Length: 687
• Identity: 301/687 - (43%)
• Similarity: 398/687 - (57%)
• Gaps: 49/687 - (7%)

  Fly     1 MAKTPPLR---PHGNMAKFLAALGICSWLLVSAT-AHNCQHQHPKAHEVVHGVRIQLADSEDDSA 61
            ||..|..|   .|.....:|..||....|.|..| |.:|:|:.|...|||:.|
 Frog     1 MAAGPGRRGTLEHWGCPAWLLTLGALFLLCVCYTGAAHCRHRAPAPREVVYKV------------ 53

  Fly    62 GDPARHSVRRRSVAAEQPLRILLVYDESVYRLEEEKFNLINDTVLPEAVQFWEQALMVRETKGVI 126
            ...:.|.::|. ||.:  ||:..|||:|:..|..||..|:.:.:.|:|:.:.:....||:....:
 Frog    54 PQKSNHKLKRH-VAPQ--LRVQTVYDKSIESLTLEKRRLVKNKLFPQAISYLQMTFQVRKPSSSV 115

  Fly   127 RLNRKCDSTQVYVK---NGHTHCIDHCKATTMCGEVQVPDAHLDVCRVCNATGQNCRIDSNTQPG 188
            .|:|:| :|..|:|   :.|.:|...|..:|.||.|.||:.||..||||:.|..:|. .|....|
 Frog   116 LLSRQC-ATNQYLKKRDDPHRYCHGACSESTRCGPVIVPEEHLQQCRVCSETQWHCG-PSGPPDG 178

  Fly   189 EGIENADFVFYVSARQTQRCFKGLTVAYAAHCQQEAALDRPIAGHANLCPESISTKPQELQTLIS 253
            .||.:.|||.||||..|:||.:...|||||:||.||.:||||||:|||||..|||:|||...::|
 Frog   179 PGIPDTDFVLYVSAMTTERCSQENIVAYAAYCQLEAEMDRPIAGYANLCPNMISTQPQEFVGMLS 243

  Fly   254 TVKHEILHALGFSVSLYAFFRDDDGKPRTPRKLDTGKPYLNEKLQIHQWSNETIRKVVRENWSVR 318
            ||||||:||||||..|:||:.||||.|.|||.:: |.||.||....:||||:.:|.|.|. |.||
 Frog   244 TVKHEIIHALGFSAGLFAFYYDDDGNPLTPRYIN-GLPYFNESRGFYQWSNKVVRMVQRV-WDVR 306

  Fly   319 GGHVNKV----VDMMVTPRVIAEVRAHFNCNKLEGAELEDQGGEGTALTHWEKRILENEAMTGTH 379
            |   .|.    |.::|||||..|.|.||:|..|||.|||:|||.||.|.|||||:||||||||:|
 Frog   307 G---QKTLPHNVFLLVTPRVTEEARKHFDCPILEGMELENQGGIGTELNHWEKRLLENEAMTGSH 368

  Fly   380 TQSPVFSRITLALMEDSGWYRANYSMATPLTWGKGLGCAFAMRSCKDWIQYNHARGRSIHPFCSK 444
            ||:.||||||||||||:||||||||||..|.||:|.||.|||:|||.||.....:.:.:.|||..
 Frog   369 TQNRVFSRITLALMEDTGWYRANYSMAERLDWGRGQGCDFAMKSCKFWIDKLKRKNQRLSPFCDT 433

  Fly   445 VKQDPLQTECTDDRNSVALCNLIRHEFELPKGYQNFDSLNHVKDGEEGFYGGSVSLADHCPYIQE 509
            |:.:|||..|..|:.:||:|||.|....||:.||.||.:..|...:...|||:|.:||.||:.||
 Frog   434 VRSNPLQLTCRQDQKAVAICNLQRFASPLPQEYQYFDDIPGVLADDLPHYGGAVEIADFCPFAQE 498

  Fly   510 FTWRSKNVIVRGSHCRFTENNPRPEKNFALESYGEGAKCFDHSESMWEERSCHQTREWQHWGSGC 574
            |.|.......|.|.||..||.|...||:..|.||.|:.|.:...:...|: |.:...:..|||||
 Frog   499 FRWHQSGEFQRSSDCRAPENQPASSKNYGAERYGPGSACLEQRSAFVMEQ-CTKRMSYPDWGSGC 562

  Fly   575 YKYDCFDGRLHILVGNYSYKCSFPGQKLSIRIAANGWLHKGAIMCPPCHELCGAQFAAQGKQCRP 639
            |:..|.:..|.:.|.:..|.|:..||.|.:|:..|.||:.|.::||||.:.|        :.|.|
 Frog   563 YQVSCTEDGLQVWVHDTPYLCTKWGQILRVRVQMNAWLYDGNLVCPPCPDFC--------EMCPP 619

  Fly   640 GEEPDPLNKYPRDNLACGAGSEK-SRSVAIITAVLLL 675
            ..:|      |.||.:..|..:. |.|..::..:.||
 Frog   620 ERDP------PLDNRSRAAPLDLCSHSPNLVVTLRLL 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Invadolysin	NP_652072.1	Peptidase_M8	93..628	CDD:302875	261/541 (48%)
lmln	XP_031749166.1	Peptidase_M8	82..614	CDD:388572	260/539 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	331	1.000	Domainoid score	I1156
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	543	1.000	Inparanoid score	I1147
OMA	1	1.010	-	-		QHG48900
OrthoDB	1	1.010	-	-		D1310134at2759
OrthoFinder	1	1.000	-	-		FOG0006130
OrthoInspector	1	1.000	-	-		oto103941
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4421
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.980