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Protein Alignment ODC1 and Odc2

DIOPT Version :9

Sequence 1:	NP_001274118.1	Gene:	ODC1 / 4953	HGNCID:	8109	Length:	461	Species:	Homo sapiens
Sequence 2:	NP_477053.2	Gene:	Odc2 / 35767	FlyBaseID:	FBgn0013308	Length:	393	Species:	Drosophila melanogaster

Alignment Length:	404	Identity:	164/404 - (40%)
Similarity:	237/404 - (58%)	Gaps:	27/404 - (6%)

- Green bases have known domain annotations that are detailed below.

Human     6 NEEFDCHFLDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKC 70
            |.:....:.||....:.:::|.  ::...|  .|..:.||..:.:|...|.|.:||:.|.|||||
  Fly     3 NGDLRIQYYDEELNIRKVIEQA--DLEHLD--QALNICDLSSLERKLRLWHKLMPRIEPHYAVKC 63

Human    71 NDSKAIVKTLAATGTGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQIKYAANNGVQMMTFDS 135
            ||...:||.||..|||||||||.|::||..|||.|||||:|:||:..|.::||....|...|.|:
  Fly    64 NDDPVVVKFLADLGTGFDCASKNELKLVLGLGVSPERIIFAHPCRPASHLRYAKEQQVVNGTVDN 128

Human   136 EVELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLRT-SRLLLERAKELNIDVVGVSFHVG 199
            |.|:.|:.:.:|.:.|::|..::..||:|.|..|:|..... :..|:..||.|.:.|.|.|||||
  Fly   129 EYEIYKLRKHYPDSNLIVRFKSEAKKALCPLGDKYGCDAEADAAALMLLAKALGLKVTGTSFHVG 193

Human   200 SGCTDPETFVQAISDARCVFDMGAEVGFSMYLLDIGGGFPGSEDVKLKFEEITGVINPALDKYFP 264
            |||::.|.:.:||..|..:|.:|..:|..|.|||:||||||.:|.  .||||...:|.:::..||
  Fly   194 SGCSEVEAYDRAIEKAENIFKVGEMIGHKMELLDVGGGFPGIDDE--MFEEIAQSVNTSVELRFP 256

Human   265 SDSGVRIIAEPGRYYVASAFTLAVNIIAKKIVLKEQTGSDDEDESSEQTFMYYVNDGVYGSFNCI 329
             |..:|||:||||::|.:|:||...:.||:.| :.:.|..|       |.|||:|||::|:|..:
  Fly   257 -DKRIRIISEPGRFFVEAAYTLICKVHAKREV-RSKDGKLD-------TMMYYLNDGIFGAFAGM 312

Human   330 LYDHAHVKPLL-----QKRPKPDEKYYSSSIWGPTCDGLDRIVERCDLPEMHVGDWMLFENMGAY 389
            .|....|.|.|     :..||     ..|.||||:||.:|:|.:.. ||.::.||.:.|.|||||
  Fly   313 FYYPEEVAPELYLDEAESLPK-----LKSVIWGPSCDAMDKISDLL-LPNLNPGDLLGFRNMGAY 371

Human   390 TVAAASTFNGFQRP 403
            |:..||.||||..|
  Fly   372 TMPIASPFNGFDVP 385

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.