Protein Alignment fs(2)ltoPP43 and IWR1

DIOPT Version :10

• Sequence 1: NP_524940.1
• Gene: fs(2)ltoPP43 / 49505
• FlyBaseID: FBgn0004811
• Length: 367
• Species: Drosophila melanogaster
• Sequence 2: NP_010168.4
• Gene: IWR1 / 851442
• SGDID: S000002273
• Length: 353
• Species: Saccharomyces cerevisiae
• Alignment Length: 387
• Identity: 81/387 - (20%)
• Similarity: 160/387 - (41%)
• Gaps: 97/387 - (25%)

  Fly     2 PAVVRIKRRIDEEPQTAFVLNGKRRRLHNDENALEDAGAVAGAVAGAVASDKDELTTVLKFAGTL 66
            |..:|:|||.||:...|.::: :.:|:...:...:.:..|:   :.:..|:::..|.:||.|
Yeast    10 PEFIRVKRRRDEDSVQALLID-EGKRVKKQKFIFKLSKTVS---SESYQSEQESSTPLLKLA--- 67

  Fly    67 EKQDDCATRKFAAARLNKAAARDLVQQQRSNDAAIASALRRDRQRQEAQENSREQRFRVVNCLRS 131
              .:|               .|..|.:||.            :.|:::.:...:||.....   |
Yeast    68 --HED---------------HRHFVLEQRK------------KSRRDSDDEKSQQRLAAEG---S 100

  Fly   132 TLENSAAEAECPESQSHESSSHITIVDIESQ---QQQHMGTASAAAEEQQQQEIAPSQDQQQPAD 193
            |:::.....|..:..:.....:..:...|.:   ::...|.::..|.       .||.|
Yeast   101 TVDDDGLPPEINQMVNDYLKLNKGVEKTERKKPSRKYFTGDSAKIAS-------LPSLD------ 152

  Fly   194 SDVGYVYDLY----VPENEMQAAYVDMMDDNYLSVIPVGEIVLEDCYNDQDEDYDSEDSNQENYF 254
                ||:|:|    :.::|: |.|.:..:..::.:|...::.|::..:..:...|.||||.|||:
Yeast   153 ----YVFDIYHLEKIHDDEV-ARYNNEKNIGFVKIIEHIDLALDEESDPNEARSDDEDSNDENYY 212

  Fly   255 TNDYP---DDDEAGAMGSD-DELCRQMNKFMLDDDEDEFASTSDDDDYATFRDPYVHTIDTEEDS 315
            .||||   |||.:...||: :::.....:.::..::..|:|.:|                   |.
Yeast   213 QNDYPEDEDDDRSILFGSEGEDIAALGEEIVIGVNKSRFSSWND-------------------DK 258

  Fly   316 FVDDVDFYNVDRERGSAYERY--KRRILK--------ELEGQEEEDEDDDDDDDSFASADGE 367
            ......:::|:.|.|..:.|.  |..:||        :|:|||.|.|..|::|||....|.|
Yeast   259 IQGSNGYHDVEEEYGDLFNRLGGKSDVLKSINSSNFIDLDGQEGEIEISDNEDDSDEGDDIE 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fs(2)ltoPP43	NP_524940.1	Iwr1	198..262	CDD:430085	22/70 (31%)
IWR1	NP_010168.4	Iwr1	152..220	CDD:430085	22/78 (28%)