DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)37Bb and foxred1

DIOPT Version :9

Sequence 1:	NP_536791.1	Gene:	l(2)37Bb / 49427	FlyBaseID:	FBgn0002021	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_001107050.1	Gene:	foxred1 / 556387	ZFINID:	ZDB-GENE-080204-64	Length:	492	Species:	Danio rerio

Alignment Length:	490	Identity:	202/490 - (41%)
Similarity:	285/490 - (58%)	Gaps:	54/490 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 EKVPIPTQSQFHFSGERDKSKEATVPDDFQT--------------------------HCDVLIIG 104
            :|.|.   ..|..|...||.....|.|.|:.                          ..||:|||
Zfish    15 QKAPC---RSFKSSRRSDKDVFEEVEDQFRAFRKKAVKAMPGSDWSPFELTPGLPPERADVVIIG 76

  Fly   105 GGGVGSSIAYWL--KEKARDGLNVVVVEKDDTYAQSATRVSVGGLCQQFSLPENIQMSLFAADFL 167
            ||.||.|||||:  ||:.|..|.|||||||.||:|::|.:|.||:.|||||.|||.:||.:||||
Zfish    77 GGVVGWSIAYWIKRKERTRGALRVVVVEKDPTYSQASTVLSCGGIRQQFSLKENILLSLESADFL 141

  Fly   168 RSARKHF----GEEVPLQFTPHGHLMLAGEEHAESLKRSSQLQNELGARNELLTADRLTARFPWL 228
            |:..||.    .:.|.|||...|:|.||.|:.|..::.:...|...||:..||:..:|..||||:
Zfish   142 RNINKHLWVTNEDPVDLQFNHSGYLFLASEKSAHVMEENYSTQRYAGAKVVLLSPSQLKERFPWM 206

  Fly   229 NTKGIALGCLGLEKEGWFNPLALLSNFRRSASGYGAHFISGQVVDFEFKSQTDISVVTDLGSNEG 293
            ||:|:||..||||.||||:|.:||:.|||.|...|.:...|:|..|.:.:|  |:.|.     ||
Zfish   207 NTEGVALASLGLENEGWFDPWSLLNAFRRKALSMGVYQCFGEVTGFRYSTQ--IAEVA-----EG 264

  Fly   294 AYTGLE--KAV-IQLPDGTR-RTCKFALCVISAGASSEQIARLARIGVGP--GILRVPLPINARK 352
            .:....  |.| :::|:... :..:..:.|.:|||:|.:||.:..||:||  .:..:|.|:..||
Zfish   265 DFVDFRRIKCVNVRMPNSLEYQPVECPVVVNAAGANSGKIAAMLGIGLGPEESVSGIPFPVEPRK 329

  Fly   353 RYMYAINSQAQSAPGMNMPMTIDPSGIFIRRDGLGGNYIC--VQDSTEE--YNSAMIDPQYFAQH 413
            |::|.::  ....||::.|..||.||:::||:|||||||.  ..:.|||  .::..:|.::|.:.
Zfish   330 RFVYVVH--CPDGPGLDTPFLIDYSGVYLRREGLGGNYIAGMSPEETEEPDISNLDVDHEFFQEK 392

  Fly   414 IRPHLYNRIPVLGEAQVVDSWAGCYDHNVYDENGILGAHPYYNNLYLATGFSGHGVQQSLAVGRA 478
            :..||.:|||...:.:|..:|||.||:|.:|:|||||.||...|:|.||||||||:|||.|||||
Zfish   393 VWHHLAHRIPAFEKLKVSSAWAGFYDYNTFDQNGILGLHPLVANMYFATGFSGHGLQQSPAVGRA 457

  Fly   479 ISELIMDGQFRTIDLSRLSFDRLIVDQPMFELNNV 513
            |:|||:|..::|||||.....|:|..:|:.|.|.|
Zfish   458 IAELILDRGYKTIDLSAFGIKRIIKKKPILERNIV 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Bb	NP_536791.1	DadA	113..501	CDD:223737	176/403 (44%)
foxred1	NP_001107050.1	DadA	83..476	CDD:223737	178/401 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586490
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9712
Inparanoid	1	1.050	380	1.000	Inparanoid score	I2025
OMA	1	1.010	-	-		QHG62229
OrthoDB	1	1.010	-	-		D393377at33208
OrthoFinder	1	1.000	-	-		FOG0003481
OrthoInspector	1	1.000	-	-		otm26567
orthoMCL	1	0.900	-	-		OOG6_105163
Panther	1	1.100	-	-	O	PTHR13847
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3938
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910