DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment l(2)37Bb and Sardh

DIOPT Version :9

Sequence 1:	NP_536791.1	Gene:	l(2)37Bb / 49427	FlyBaseID:	FBgn0002021	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_611263.1	Gene:	Sardh / 37026	FlyBaseID:	FBgn0034276	Length:	894	Species:	Drosophila melanogaster

Alignment Length:	425	Identity:	96/425 - (22%)
Similarity:	168/425 - (39%)	Gaps:	78/425 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 DVLIIGGGGVGSSIAYWLKEKARDGLNVVVVEKDDTYAQSATRVSVGGLCQQFSLPENIQMSLFA 163
            ||::||||..|....|.|   ||.|:..|::|:....|  .|.....||..:.. |.::.:.|.|
  Fly    38 DVVVIGGGSAGCHTLYHL---ARRGVKAVLLERAQLTA--GTTWHTAGLLWRLR-PNDVDIQLLA 96

  Fly   164 ADFLRSARKHFGEEVPLQ--FTPHGHLMLA-GEEHAESLKRSSQLQNELGARNELLTADRLTARF 225
            ..  |...:...||..|.  :..:|.:.:| .|...:..:|.:.:.:.||..|::|:.:.....|
  Fly    97 NS--RRMLQQLEEETELDPGWIQNGGIFIAHNETRLDEYRRLATVGSALGIENQVLSPEDTQKLF 159

  Fly   226 PWLNTKGIALGCLGLEKEGWFNPLALLSNFRRSASGYGAHFISGQVVDFEFKSQTDISVVTDLGS 290
            |.|:.... :|.|....:|..:|..|.:..:::|:..||..|....||.....||
  Fly   160 PLLDPSAF-VGALYSPGDGVMDPAMLCAALKKAATNLGAQVIENCGVDDLLLEQT---------- 213

  Fly   291 NEGAYTGLEKAVIQLPDGTRRTCKFALCVISA-GASSEQIARLARIGVGPGILRVPL-PINARKR 353
                ..|.:...:..|.|..:..|    |::| |.....:  :||.|.     .:|| |:    :
  Fly   214 ----ARGKKVVGVSTPFGDIKAEK----VVNATGVWGRDL--VARHGT-----HLPLVPM----K 259

  Fly   354 YMYAINSQAQSAPGM-NMPMTIDPS-GIFIRRDG----LGG---NYICVQDSTEEYNSAM--IDP 407
            :.|.:   ::|.||: .:|...|.. ..:.|..|    :||   |.|.::...::::..:  :|.
  Fly   260 HAYIV---SESIPGVRGLPNIRDHDYSTYFRIQGDAICMGGYEPNPILLEPVPKDFHFGLYELDW 321

  Fly   408 QYFAQHIRPHLYNRIPVLGEAQVVDSWAG-------CYDHN-VYDENGILGAHPYYNNLYLATGF 464
            ..|..|:.          |..::..|:|.       |...: ..|...::|..|..:.||...||
  Fly   322 SVFETHVE----------GAQKLCPSYAKYGVKSTVCGPESFTPDHKPLMGPDPNLDGLYHNCGF 376

  Fly   465 SGHGVQQSLAVGRAISELIMDGQFRTIDLSRLSFD 499
            :..|:......|...:..::.||   .||....||
  Fly   377 NSAGMMFGGGCGEQTALWVIQGQ---PDLPMFGFD 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Bb	NP_536791.1	DadA	113..501	CDD:223737	89/411 (22%)
Sardh	NP_611263.1	DadA	33..412	CDD:223737	96/425 (23%)
		NADB_Rossmann	37..>76	CDD:304358	16/42 (38%)
		nuc_hydro	203..>281	CDD:294156	23/109 (21%)
		FAO_M	398..449	CDD:292961	6/14 (43%)
		GcvT	446..884	CDD:223481
		GCV_T	456..767	CDD:279857
		GCV_T_C	774..867	CDD:285832
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456420
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR13847
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940