Protein Alignment l(2)37Bb and L2HGDH

DIOPT Version :9

• Sequence 1: NP_536791.1
• Gene: l(2)37Bb / 49427
• FlyBaseID: FBgn0002021
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_001286076.1
• Gene: L2HGDH / 35156
• FlyBaseID: FBgn0032729
• Length: 455
• Species: Drosophila melanogaster
• Alignment Length: 460
• Identity: 91/460 - (19%)
• Similarity: 159/460 - (34%)
• Gaps: 142/460 - (30%)

  Fly    99 DVLIIGGGGVGSSIAYWLKEKARD------GLNVVVVEKDDTYAQSATRVSVG----GLCQQFSL 153
            |::::|||.||::       .||:      .|.|.|:||:...|:..:..:.|    |:   :..
  Fly    44 DLVVVGGGIVGAA-------SAREIVLRHPSLKVAVLEKECKLAKHQSGHNSGVIHAGI---YYK 98

  Fly   154 PENIQMSLFAADFLRSARKHFGE-EVPLQFTPHGHLMLAGEEHAESLKRSSQLQNELGARN---- 213
            |..::..| ..:.:..|..:..| ::|.:.|  |.|::|.:|  :.:|....|:....|.|
  Fly    99 PGTLKARL-CVEGMHLAYAYLDEKKIPYKKT--GKLIVATDE--KEVKLLKDLEKRGIANNVPDL 158

  Fly   214 ELLTADRLTARFPWLNTKGIALGCLGLEKEGWFNPLALLSNFRRSASGYGAHF--ISGQV-VDF- 274
            .::....:....|:..      |.:.|.     :|...:.::......||..|  ..|.: :||
  Fly   159 RMIEGSEIQEIEPYCQ------GVMALH-----SPHTGIVDWGLVTEHYGQDFKQCGGDIYLDFN 212

  Fly   275 -----EFKSQTDISVVTDLGSNEGAYTGLEKAVIQLPDGTRRTCKFALCVISAGASSEQIARLAR 334
                 |.|..||..|..     .||          .|..|.||.....|   .|..|:.:|...
  Fly   213 VSKFTETKEGTDYPVTI-----HGA----------KPGQTVRTKNVLTC---GGLQSDLLAEKT- 258

  Fly   335 IGVGPGILRVPLPINARKRYMYAINSQAQSAPGMNMPMTIDPSGIFI------RRDG---LGGNY 390
                 |..|.|..:..|..|:.....:.....|...|:. ||...|:      |.||   ||.|.
  Fly   259 -----GCPRDPRIVPFRGEYLLLTKEKQHMVKGNIYPVP-DPRFPFLGVHFTPRMDGSIWLGPNA 317

  Fly   391 ICVQDSTEEYNSAMIDPQYFAQHIRPHLYNRIPVLGEAQVVDSWAGCYDHNVYDENGILGAHPYY 455
            :... ..|.|                                :|.   |.|:::   :..|..|.
  Fly   318 VLAL-KREGY--------------------------------TWG---DINLFE---LFDALRYP 343

  Fly   456 NNLYLATGFSGHGVQQ-------SLAVGRAISELIMDGQFRTIDLSR---------LSFDRLIVD 504
            ..:.:|:.:.|.|:.:       :|.: :|:.:.|.|  ....|:.|         :..|..:||
  Fly   344 GFVKMASKYIGFGLSEMSKSWFINLQI-KALQKYIPD--ITEYDIQRGPAGVRAQAMDLDGNLVD 405

  Fly   505 QPMFE 509
            ..:|:
  Fly   406 DFVFD 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Bb	NP_536791.1	DadA	113..501	CDD:223737	82/436 (19%)
L2HGDH	NP_001286076.1	PRK11728	56..447	CDD:183292	85/448 (19%)
		NADB_Rossmann	69..440	CDD:304358	82/428 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456422
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930