DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)37Bb and Pdpr

DIOPT Version :9

Sequence 1:	NP_536791.1	Gene:	l(2)37Bb / 49427	FlyBaseID:	FBgn0002021	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_001100900.1	Gene:	Pdpr / 307852	RGDID:	1308307	Length:	878	Species:	Rattus norvegicus

Alignment Length:	469	Identity:	96/469 - (20%)
Similarity:	179/469 - (38%)	Gaps:	119/469 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 ETEKVPIPTQSQFHFSGERDKSKEATVPDDFQTHCDVLIIGGGGVGSSIAYWLKEKARDGLNVVV 128
            |.:.:.:|.|:|                        |:|.|||.:|:|:||.|   ::.|...:|
  Rat    32 EAQSIALPAQAQ------------------------VVICGGGIMGTSVAYHL---SKMGWQDIV 69

  Fly   129 VEKDDTYAQSATRVSVGGLCQQFSLPENIQMSLFAADFLRSARKHFGEEVPLQ--FTPHGHLMLA 191
            :.:....|..:||...|.|    |...:..:....||:.........:|..:|  :...|.:.||
  Rat    70 LLEQGRLAAGSTRFCAGIL----STARHSSIEQKMADYSNKLYHQLEQETGIQTGYLRTGSISLA 130

  Fly   192 -GEEHAESLKRSSQLQNELGARNELLTADRLTARFPWLNTKGIALGCLGLEKEGWFN----PLAL 251
             .::...||||.:...|.:|..:|:::..::....|.||...: :|.:.:.::...:    .|||
  Rat   131 QTQDRLISLKRINSRLNVVGIPSEIISPKKVAELHPLLNVHDL-VGAMHVPEDAVVSSADVALAL 194

  Fly   252 LSNFRRSASGYGAHFISGQVVDFEFKSQTDISVVTDLGSNEGAYTGLEKAVIQLPDGTRRTCK-F 315
            .|    :||..|.     |:.|     :|.:..|.   :.:|..||::      .|..:..|: |
  Rat   195 AS----AASQNGV-----QIYD-----RTSVLHVL---TKKGRVTGVD------TDKGQIECQYF 236

  Fly   316 ALC----VISAGASSEQIARLARIGVGPGILRVPLPINARKRYMYAINSQAQSAPGMNMPMTIDP 376
            ..|    ....|.|||:              .|.:|::|.:.: |.:.....:....:.|..:|.
  Rat   237 VNCAGQWAYELGLSSEE--------------PVSIPLHACEHF-YLLTRPCDAPLQSSTPTVVDA 286

  Fly   377 SG-IFIR--RDGL---------------GGNYICVQDSTEEYNSAMIDPQYFAQHIRP---HLYN 420
            .| |:||  :.|:               |.|.:.:|:..|:::           |..|   .|..
  Rat   287 DGRIYIRNWQGGVLSGGFEKNPKPIFTEGKNQLEIQNLREDWD-----------HFEPLLSSLLR 340

  Fly   421 RIPVLGEAQVVDSWAGCYDHNVYDENGILGAHPYYNNLYLATGFSGHGVQQSLAVGRAISELIMD 485
            |:|.|...::: ....|.:....|...|:|..|.....::..|.:..|:......|:.::|.::.
  Rat   341 RMPGLESVEIL-KLVNCPETFTADMKCIMGESPVVQGYFVLAGMNSAGLSLGGGAGKLLAEWMVY 404

  Fly   486 G----QFRTIDLSR 495
            |    ....:||.|
  Rat   405 GYPSENVWELDLQR 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Bb	NP_536791.1	DadA	113..501	CDD:223737	85/420 (20%)
Pdpr	NP_001100900.1	DAO	44..384	CDD:279590	85/397 (21%)
		FAO_M	405..459	CDD:292961	4/14 (29%)
		GcvT	452..867	CDD:223481
		GCV_T	462..735	CDD:279857
		GCV_T_C	747..851	CDD:285832
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345430
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840