DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)37Bb and Y37E3.17

DIOPT Version :9

Sequence 1:	NP_536791.1	Gene:	l(2)37Bb / 49427	FlyBaseID:	FBgn0002021	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_001360456.1	Gene:	Y37E3.17 / 171775	WormBaseID:	WBGene00021355	Length:	840	Species:	Caenorhabditis elegans

Alignment Length:	465	Identity:	117/465 - (25%)
Similarity:	182/465 - (39%)	Gaps:	96/465 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 IPTQSQFHFSGERDKSKEATVPDDFQTHCDVLIIGGGGVGSSIAYWL-KEKARDGLNVVVVEK-- 131
            |.|.|..|.|.....|.:         |....::|.|..|||:||.| |...:|   |:::|:
Worm     9 IRTSSDLHTSIRNSSSTK---------HVFACVLGSGVAGSSVAYHLTKRNIKD---VLLLERAS 61

  Fly   132 DDTY------AQSATRVSVGGLCQQFSLPENIQMSLFAADFLRSARKHFGEEVPLQFTPHGHLML 190
            |..:      :.|.|.....||... |.|.:....:.|......::......|.:.|.|.|.:.|
Worm    62 DGDFGVHGVASPSGTSFHSPGLVSA-SHPAHRYKPILAHSIELYSKLEAETGVNIDFQPTGTIRL 125

  Fly   191 AGEEH--AESLKRSSQLQNELG--ARNELLTADRLTARFPWLNTKGIALGCLGLEKEGWFNPLAL 251
            |..|.  ||..|..::...:.|  .:..|||.|::....|.::...| ||.|....:|..:..||
Worm   126 ATNETRLAEFRKYVNRDYYKEGDVCKTTLLTPDQVRELAPDVDHSKI-LGALHTTNDGTISARAL 189

  Fly   252 LSNFRRSASGYGAHFISGQVVDFEFKSQTDISVVTDLGSNEGAYTGLEKAVIQLPDGTRRTCKFA 316
            .......|...||..|.| .:..|.|...:          :|.:      :|.|.|||..|.:
Worm   190 TQALVVGAKNGGAQVIDG-AIPKEIKYDKE----------KGHW------IIALEDGTLVTTR-- 235

  Fly   317 LCVISAGAS-SEQIARLARIGVGPGILRVPLPINARKRYMYAINSQAQSAPGMNMPMTID-PSGI 379
             .:|:||.. :..||||:...         ||: ....:.||:.: ....||.. |..|| .|..
Worm   236 -NLINAGGIWANDIARLSGHA---------LPV-VVVEHQYAVLT-PNKTPGPT-PAIIDHDSTF 287

  Fly   380 FIRRDG---LGGNYICVQDS------------TEEYNSAMIDPQYFAQHIRPHLYNR----IPVL 425
            ::|:.|   |.|.:..::.:            ||...|...|   |::  ....|.|    ||.|
Worm   288 YVRKSGDDYLFGGFESLEKTVIREDWYKKGVPTEGSKSIQAD---FSR--LDDAYKRACDLIPGL 347

  Fly   426 GEAQVVDSWAGCYDHNVYDENGILGAHPYYNNLYLATGFSGHGVQQSLAVGRAISELIMDGQ--- 487
             :...||:.|..:.... |...::|  ||..|.:::|||. .||.....:|:.:::.|:||:
Worm   348 -QGSKVDARAAVFSMTP-DGYPLVG--PYDKNYWMSTGFL-DGVSSGGGIGKYLADWIVDGEPPA 407

  Fly   488 --FRTIDLSR 495
              |.| |.||
Worm   408 ELFDT-DASR 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Bb	NP_536791.1	DadA	113..501	CDD:223737	105/422 (25%)
Y37E3.17	NP_001360456.1	DadA	26..421	CDD:223737	111/448 (25%)
Y37E3.17	NP_001360456.1	GcvT	447..838	CDD:223481
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D752680at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920